Hardware-in-the-loop simulation of vascular cannula interaction *

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, vol. 41, pp. 1–4

Abstract

Traditionally, the functional development, testing and verification of higher level automation, control and safety functions in extracorporeal circulations systems relies very much on the conduction of animal experiments. This especially applies to functions requiring interaction with the patients physiology. Besides ethical aspects, animal experiments have the disadvantage of higher complexity, limited reproducibility and certain pathological conditions can only be represented with difficulty. An alternative to this can be Hardware-in-the-loop (HIL) simulators.In this paper we present a HIL solution to simulate the hydraulic interaction between the cannula and the connected blood vessel. We derive a hydraulic model for an elastic vessel with particular emphasis on negative transmural pressure. In this case the resistance is mainly determined by collapse phenomena. The next section describes the design of an universal resistance actuator that can simulate vascular resistances in the expected range. Combined in the HIL simulator, the simulation model then generates the setpoint for the actuator while simultaneously receiving the resulting internal states of the hydraulic interface. This creates a truly interactive HIL simulator where the device under test interacts in the same way as with a physiological system.

Authors 5

1. Marian Walter Aachen Institute for Medical Information Technology Faculty of Electrical Engineering and Information Technology

   RWTH Aachen University

   Affiliation as printed

   RWTH Aachen University,Institute for Medical Information Technology, Faculty of Electrical Engineering and Information Technology,Aachen,Germany,52074

2. Andreas Puschke Aachen Institute for Medical Information Technology Faculty of Electrical Engineering and Information Technology

   RWTH Aachen University

   Affiliation as printed

   RWTH Aachen University,Institute for Medical Information Technology, Faculty of Electrical Engineering and Information Technology,Aachen,Germany,52074

3. Cavan Lübke Aachen Department of Intensive Care Medicine and Intermediate Care

   Universitätsklinikum Aachen · RWTH Aachen University

   Affiliation as printed

   Uniklinik RWTH Aachen University,Department of Intensive Care Medicine and Intermediate Care (OIM),Aachen,Germany,52074

4. Rüdger Kopp Aachen Department of Intensive Care Medicine and Intermediate Care

   Universitätsklinikum Aachen · RWTH Aachen University

   Affiliation as printed

   Uniklinik RWTH Aachen University,Department of Intensive Care Medicine and Intermediate Care (OIM),Aachen,Germany,52074

5. Steffen K. Leonhardt Aachen Institute for Medical Information Technology Faculty of Electrical Engineering and Information Technology

   RWTH Aachen University

   Affiliation as printed

   RWTH Aachen University,Institute for Medical Information Technology, Faculty of Electrical Engineering and Information Technology,Aachen,Germany,52074