ENLIGHT: A consensus checklist for reporting laboratory-based studies on the non-visual effects of light in humans
EBioMedicine, vol. 98, pp. 104889
Abstract
BACKGROUND: There is no consensus on reporting light characteristics in studies investigating non-visual responses to light. This project aimed to develop a reporting checklist for laboratory-based investigations on the impact of light on non-visual physiology. METHODS: A four-step modified Delphi process (three questionnaire-based feedback rounds and one face-to-face group discussion) involving international experts was conducted to reach consensus on the items to be included in the checklist. Following the consensus process, the resulting checklist was tested in a pilot phase with independent experts. FINDINGS: An initial list of 61 items related to reporting light-based interventions was condensed to a final checklist containing 25 items, based upon consensus among experts (final n = 60). Nine items were deemed necessary to report regardless of research question or context. A description of each item is provided in the accompanying Explanation and Elaboration (E&E) document. The independent pilot testing phase led to minor textual clarifications in the checklist and E&E document. INTERPRETATION: The ENLIGHT Checklist is the first consensus-based checklist for documenting and reporting ocular light-based interventions for human studies. The implementation of the checklist will enhance the impact of light-based research by ensuring comprehensive documentation, enhancing reproducibility, and enabling data aggregation across studies. FUNDING: Network of European Institutes for Advanced Study (NETIAS) Constructive Advanced Thinking (CAT) programme; Sir Henry Wellcome Postdoctoral Fellowship (Wellcome Trust, 204686/Z/16/Z); Netherlands Organisation for Health Research and Development VENI fellowship (2020-09150161910128); U.S. Department of Defense Grant (W81XWH-16-1-0223); National University of Singapore (NUHSRO/2022/038/Startup/08); and National Research Foundation Singapore (NRF2022-THE004-0002).
Authors 61
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Manuel Spitschan corresponding
Max Planck Institute for Biological Cybernetics · TUM CREATE · Technical University of Munich
Affiliation as printed
TUM School of Medicine & Health, Department of Health and Sport Sciences, Technical University of Munich, Munich, Germany; TUM Institute for Advanced Study (TUM-IAS), Technical University of Munich, Garching, Germany; Max Planck Institute for Biological Cybernetics, Max Planck Research Group Translational Sensory & Circadian Neuroscience, Tübingen, Germany; TUMCREATE, Singapore, Singapore. Electronic address: manuel.spitschan@tum.de
Max Planck Institute for Biological Cybernetics, Max Planck Research Group Translational Sensory & Circadian Neuroscience, Tübingen, Germany
TUM Institute for Advanced Study (TUM-IAS), Technical University of Munich, Garching, Germany
TUM School of Medicine & Health, Department of Health and Sport Sciences, Technical University of Munich, Munich, Germany
TUMCREATE, Singapore, Singapore
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Laura Kervezee corresponding Aachen Laboratory for Neurophysiology Department of Cellular and Chemical Biology Laboratory for Neurophysiology Department of Cellular and Chemical Biology
Leiden University · Leiden University Medical Center
Affiliation as printed
Laboratory for Neurophysiology, Department of Cellular and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands. Electronic address: L.Kervezee@lumc.nl
Laboratory for Neurophysiology, Department of Cellular and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands
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Renske Lok corresponding
Affiliation as printed
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, USA. Electronic address: rlok@stanford.edu
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, USA
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Elise M. McGlashan corresponding
The University of Melbourne · Monash University
Affiliation as printed
Melbourne School of Psychological Sciences, The University of Melbourne, Parkville, Victoria, Australia; School of Psychological Science and Turner Institute for Brain and Mental Health, Monash University, Melbourne, Australia. Electronic address: elise.mcglashan@unimelb.edu.au
Melbourne School of Psychological Sciences, The University of Melbourne, Parkville, Victoria, Australia
School of Psychological Science and Turner Institute for Brain and Mental Health, Monash University, Melbourne, Australia
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Raymond P. Najjar corresponding
National University of Singapore · Singapore Eye Research Institute · Duke-NUS Medical School
Affiliation as printed
Department of Ophthalmology and Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore; Center for Innovation & Precision Eye Health, National University of Singapore, Singapore, Singapore; Singapore Eye Research Institute, Singapore, Singapore; Ophthalmology and Visual Sciences Academic Clinical Programme, Duke-NUS Medical School, Singapore, Singapore. Electronic address: rpnajjar@nus.edu.sg
Center for Innovation & Precision Eye Health, National University of Singapore, Singapore, Singapore
Department of Ophthalmology and Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore
Ophthalmology and Visual Sciences Academic Clinical Programme, Duke-NUS Medical School, Singapore, Singapore
Singapore Eye Research Institute, Singapore, Singapore
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