Artificial intelligence-based classification of motor unit action potentials in real-world needle EMG recordings
Clinical Neurophysiology, vol. 156, pp. 220–227
Abstract
OBJECTIVE: To develop an artificial neural network (ANN) for classification of motor unit action potential (MUAP) duration in real-word, unselected and uncleaned needle electromyography (n-EMG) recordings. METHODS: Two nested ANN models were trained, the first discerning muscle rest, contraction and artifacts in n-EMG recordings from 2674 individual muscles from 326 patients obtained as part of daily care. The second ANN model subsequently used segments labeled as contraction for prediction of prolonged, normal and shortened MUAPs. Model performance was assessed in one internal and two external validation datasets of 184, 30 and 50 muscles, respectively. RESULTS: The first model discerned rest, contraction and artifacts with an accuracy of 96%. The second model predicted prolonged, normal and shortened MUAPs with an accuracy of 67%, 83% and 68% in the different validation sets. CONCLUSIONS: We developed a two-step ANN that classifies rest, muscle contraction and artifacts from real-world n-EMG recordings with very high accuracy. MUAP duration classification had moderate accuracy. SIGNIFICANCE: This is the first study to show that an ANN can classify MUAPs in real-world n-EMG recordings highlighting the potential for AI assisted MUAP classification as a clinical tool.
Authors 7
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Deborah Hubers corresponding
Amsterdam UMC Location University of Amsterdam · Amsterdam Neuroscience · Amsterdam University Medical Centers
Affiliation as printed
Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands. Electronic address: d.hubers@amsterdamumc.nl
Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Amsterdam University Medical Centers, location AMC, Amsterdam, the Netherlands
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Amsterdam UMC Location University of Amsterdam · Amsterdam Neuroscience · Amsterdam University Medical Centers
Affiliation as printed
Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands
Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Amsterdam University Medical Centers, location AMC, Amsterdam, the Netherlands
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Amsterdam UMC Location University of Amsterdam · Amsterdam Neuroscience · Amsterdam University Medical Centers
Affiliation as printed
Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands
Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Amsterdam University Medical Centers, location AMC, Amsterdam, the Netherlands
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Amsterdam UMC Location University of Amsterdam · Amsterdam Neuroscience · Amsterdam University Medical Centers
Affiliation as printed
Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands
Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Amsterdam University Medical Centers, location AMC, Amsterdam, the Netherlands
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Leiden University Medical Center
Affiliation as printed
Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands
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Amsterdam UMC Location University of Amsterdam · St. Antonius Ziekenhuis · Amsterdam Neuroscience · Amsterdam University Medical Centers
Affiliation as printed
Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands; Department of Clinical Neurophysiology, St. Antonius Hospital, Nieuwegein, the Netherlands
Department of Clinical Neurophysiology, St. Antonius Hospital, Nieuwegein, the Netherlands
Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Amsterdam University Medical Centers, location AMC, Amsterdam, the Netherlands
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Amsterdam UMC Location University of Amsterdam · Amsterdam Neuroscience · Amsterdam University Medical Centers
Affiliation as printed
Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands
Department of Neurology and Clinical Neurophysiology, Amsterdam Neuroscience, Amsterdam University Medical Centers, location AMC, Amsterdam, the Netherlands
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