Hybrid Compartment Model Formulation for Accelerated Bolus Fitting

European Signal Processing Conference (EUSIPCO), pp. 1120–1124

Abstract

Curve fitting is the central step in extracting hemodynamic parameters from various contrast-based medical imaging modalities. Yet, using functions derived from compartment modelling principles with basic nonlinear least-squares approaches is challenging and computationally expensive. This contribution describes a novel hybrid approach to efficiently and accurately estimate blood flow and volume, which was compared against the state-of-the-art via extensive realistic simulations for computerized and electrical impedance tomography, having shown superior robustness, speed, and overall accuracy.

Authors 2

1. Diogo Filipe Silva Aachen Chair for Medical Information Technology

   RWTH Aachen University

   Affiliation as printed

   RWTH Aachen University,Chair for Medical Information Technology,Aachen,Germany

   Chair for Medical Information Technology, RWTH Aachen University, Aachen, Germany

2. Steffen K. Leonhardt Aachen Chair for Medical Information Technology

   RWTH Aachen University

   Affiliation as printed

   RWTH Aachen University,Chair for Medical Information Technology,Aachen,Germany

   Chair for Medical Information Technology, RWTH Aachen University, Aachen, Germany