Data from network meta-analyses can inform clinical practice guidelines and decision-making in diabetes management: perspectives of the taskforce of the guideline workshop
Cardiovascular Diabetology, vol. 22, pp. 277
Abstract
In recent years, several novel agents have become available to treat individuals with type 2 diabetes (T2D), such as sodium-glucose cotransporter-2 inhibitors (SGLT-2i), tirzepatide, which is a dual glucose-dependent insulinotropic polypeptide receptor agonist (GIP RA)/glucagon-like peptide-1 receptor agonist (GLP-1 RA), and finerenone, a non-steroidal mineralocorticoid receptor antagonist (MRA) that confers significant renal and cardiovascular benefits in individuals with (CKD). New medications have the potential to improve the lives of individuals with diabetes. However, clinicians are challenged to understand the benefits and potential risks associated with these new and emerging treatment options. In this article, we discuss how use of network meta-analyses (NMA) can fill this need.
Authors 19
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Affiliation as printed
IRCCS MultiMedica, Via Milanese 300, 20099, Sesto San Giovanni, MI, Italy
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Affiliation as printed
Endocrine and Metabolic Consultants, 3200 Tower Oaks Blvd., Suite 250, Rockville, MD, 20852, USA
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University of Ljubljana · Ljubljana University Medical Centre
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University Medical Center Ljubljana, and Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
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Affiliation as printed
University of Arizona College of Medicine, 1501 N. Campbell Ave, Tucson, AZ, 85724-5022, USA
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Karolinska University Hospital · Karolinska Institutet
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Cardiology Unit, Department of Medicine, Karolinska Institute and Karolinska University Hospital, Solna, Stockholm, Sweden
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Duke University Medical Center, Duke Clinical Research Institute, 200 Morris St, DUMC Box 3850, Durham, NC, 27715, USA
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Peking University People's Hospital
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Peking University People's Hospital, 11 Xizhimen S St, Xicheng District, Beijing, China
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Marienhospital Stuttgart, Böheimstraße 37, 70199, Stuttgart, Germany
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PCNA National Office, 613 Williamson Street, Suite 200, Madison, WI, 53703, USA
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UNSW Sydney · The George Institute for Global Health · Saint Luke's Hospital · University of Missouri–Kansas City
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Saint Luke's Mid America Heart Institute and University of Missouri-Kansas City, 4401 Wornall Rd, Kansas City, MO, 64111, USA
The George Institute for Global Health and University of New South Wales, Sydney, Australia
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University of Belgrade · Univerzitetski Klinički Centar Srbije
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University Clinical Center of Serbia, University of Belgrade, Pasterova 2, 11000, Belgrade, Serbia
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Universitätsklinikum Aachen · RWTH Aachen University
Affiliation as printed
Department of Internal Medicine I, University Hospital Aachen, RWTH Aachen University, Pauwelsstraße 30, 52074, Aachen, Germany
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American Heart Association, 7272 Greenville Avenue, Dallas, TX, 75082, USA
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CGParkin Communications, Inc., 2675 Windmill Pkwy, Suite 2721, Henderson, NV, 89074, USA
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Affiliation as printed
Department of Medicine K2, Karolinska Institute, Stockholm, Sweden
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National Health Research Institutes
Affiliation as printed
Institute of Molecular and Genomic Medicine, National Research Health Institutes, Zhunan, Miaoli, 350, Taiwan
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Affiliation as printed
Forschergruppe Diabetes E. V, Ingolstaedter Landstraße 1, Neuherberg, 85764, Munich, Germany
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Affiliation as printed
Institute of Health and Society, University of Oslo, Oslo, Norway
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Oliver Schnell corresponding
Affiliation as printed
Forschergruppe Diabetes E. V, Ingolstaedter Landstraße 1, Neuherberg, 85764, Munich, Germany. oliver.schnell@lrz.uni-muenchen.de
Forschergruppe Diabetes E. V, Ingolstaedter Landstraße 1, Neuherberg, 85764, Munich, Germany
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