History-Dependent Decision-Making across Species

Conference on Cognitive Computational Neuroscience (CCN)

Abstract

Mice are increasingly used to study the neural circuitlevel basis of behavior, often with the ultimate goal to extrapolate these insights to humans.To generalize insights about neural functioning between species, it is crucial to first ensure correspondence in behavioral and cognitive strategy.Here, we analyzed decision-making behavior in both humans and mice, and identified the same cognitive strategy of history-dependent evidence accumulation.Specifically, individual differences in choice repetition were explained by a history-dependent bias in the rate of evidence accumulation -rather than its starting point.Evidence integration over multiple temporal scales thus reflects a fundamental aspect of decision-making, conserved across mammalian species.These findings set the stage for linking the computations of decision-making to neural dynamics at the single-cell and population levels.

Authors 1

1. Anne E Urai corresponding Aachen Cognitive Psychology Netherlands International Brain Laboratory

   Leiden University · International Brain Laboratory

   Affiliation as printed

   Leiden University

   Cognitive Psychology, Leiden University, The Netherlands International Brain Laboratory