Calibration-free parallel transmission for improved CSF mobility imaging at 7T

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

Abstract

Better understanding of how the brain cleans itself is of high importance as its failure has been linked to various neurodegenerative diseases. A first step towards elucidating CSF-mediated clearance mechanisms is the measurement of CSF motion in the human brain. In this work, we present an imaging sequence for CSF mobility measurements employing calibration-free parallel transmission. During the imaging session, no pulse calculations or complex B1 shimming procedures are necessary, making this approach feasible for large scale patient studies.

Authors 10

1. Philipp Ehses

   German Center for Neurodegenerative Diseases

   Affiliation as printed

   German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany

2. Lydiane Hirschler Aachen Radiology

   Leiden University Medical Center · German Center for Neurodegenerative Diseases

   Affiliation as printed

   German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany

   Radiology, Leiden University Medical Center, Leiden, Netherlands

3. Eberhard Pracht

   German Center for Neurodegenerative Diseases

   Affiliation as printed

   German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany

4. Katerina Deike‐Hofmann

   German Center for Neurodegenerative Diseases

   Affiliation as printed

   German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany

5. Vincent Gras

   Centre National de la Recherche Scientifique · Commissariat à l'Énergie Atomique et aux Énergies Alternatives · Université Paris-Saclay · CEA Paris-Saclay · Building large instruments for neuroimaging: from population imaging to ultra-high magnetic fields

   Affiliation as printed

   University of Paris-Saclay, CEA, CNRS, BAOBAB, NeuroSpin, Gif sur Yvette, France

6. Franck Mauconduit

   Centre National de la Recherche Scientifique · Commissariat à l'Énergie Atomique et aux Énergies Alternatives · Université Paris-Saclay · CEA Paris-Saclay · Building large instruments for neuroimaging: from population imaging to ultra-high magnetic fields

   Affiliation as printed

   University of Paris-Saclay, CEA, CNRS, BAOBAB, NeuroSpin, Gif sur Yvette, France

7. Aurélien Massire

   Siemens (France)

   Affiliation as printed

   Siemens Healthcare SAS, Saint-Denis, France

8. Nicolas Boulant

   Centre National de la Recherche Scientifique · Commissariat à l'Énergie Atomique et aux Énergies Alternatives · Université Paris-Saclay · CEA Paris-Saclay · Building large instruments for neuroimaging: from population imaging to ultra-high magnetic fields

   Affiliation as printed

   University of Paris-Saclay, CEA, CNRS, BAOBAB, NeuroSpin, Gif sur Yvette, France

9. Matthias J.P. van Osch Aachen Radiology

   Leiden University Medical Center

   Affiliation as printed

   Radiology, Leiden University Medical Center, Leiden, Netherlands

10. Tony Stoecker

    University of Bonn · German Center for Neurodegenerative Diseases

    Affiliation as printed

    Department of Physics and Astronomy, University of Bonn, Bonn, Germany

    German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany