Multiplexing System for Automated Characterization of a Capacitive Field‐Effect Sensor Array
physica status solidi (a), vol. 220
Abstract
In comparison to single‐analyte devices, multiplexed systems for a multianalyte detection offer a reduced assay time and sample volume, low cost, and high throughput. Herein, a multiplexing platform for an automated quasi‐simultaneous characterization of multiple (up to 16) capacitive field‐effect sensors by the capacitive–voltage (C–V) and the constant‐capacitance (ConCap) mode is presented. The sensors are mounted in a newly designed multicell arrangement with one common reference electrode and are electrically connected to the impedance analyzer via the base station. A Python script for the automated characterization of the sensors executes the user‐defined measurement protocol. The developed multiplexing system is tested for pH measurements and the label‐free detection of ligand‐stabilized, charged gold nanoparticles.
Authors 6
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Tobias Karschuck Aachen
Affiliation as printed
Institute of Nano- and Biotechnologies FH Aachen 52428 Jülich Germany
Laboratory for Soft Matter and Biophysics KU Leuven 3001 Leuven Belgium
Laboratory for Soft Matter and Biophysics, KU Leuven, 3001 Leuven, Belgium
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Stefan Schmidt Aachen
Affiliation as printed
Institute of Nano- and Biotechnologies FH Aachen 52428 Jülich Germany
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Stefan Achtsnicht Aachen
Affiliation as printed
Institute of Nano- and Biotechnologies FH Aachen 52428 Jülich Germany
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Affiliation as printed
MicroNanoBio 40479 Düsseldorf Germany
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Affiliation as printed
Laboratory for Soft Matter and Biophysics KU Leuven 3001 Leuven Belgium
Laboratory for Soft Matter and Biophysics, KU Leuven, 3001 Leuven, Belgium
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Forschungszentrum Jülich · FH Aachen
Affiliation as printed
Institute of Biological Information Processing (IBI-3) Forschungszentrum Jülich 52425 Jülich Germany
Institute of Nano- and Biotechnologies FH Aachen 52428 Jülich Germany
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