Between guidelines and clinical trials: evidence-based advice on the pharmacological management of non-specific chronic low back pain
BMC Musculoskeletal Disorders, vol. 24, pp. 432
Abstract
The pharmacological management of nonspecific chronic low back pain (NCLBP) aims to restore patients' daily activities and improve their quality of life. The management of NCLBP is not well codified and extremely heterogeneous, and residual symptoms are common. Pharmacological management should be considered as co-adjuvant to non-pharmacological therapy, and should be guided by the symptoms reported by the patients. Depending on the individual severity of NCLPB, pharmacological management may range from nonopioid to opioid analgesics. It is important to identify patients with generalized sensory hypersensitivity, who may benefit from dedicated therapy. This article provides an evidence-based overview of the principles of pharmacological management of NCLPB.
Authors 5
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Filippo Migliorini corresponding Aachen Department of Orthopaedic, Trauma, and Reconstructive Surgery
RWTH Aachen University · Universitätsklinikum Aachen · Ospedale di Bolzano · Azienda Sanitaria dell'Alto Adige
Affiliation as printed
Department of Orthopaedic and Trauma Surgery, Academic Hospital of Bolzano (SABES-ASDAA), Bolzano, 39100, Italy. migliorini.md@gmail.com
Department of Orthopaedic, Trauma, and Reconstructive Surgery, RWTH University Hospital of Aachen, 52064, Aachen, Germany. migliorini.md@gmail.com
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Affiliation as printed
Department of Orthopedics, Indraprastha Apollo Hospitals Institutes of Orthopaedics, New Delhi, India
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Affiliation as printed
Department of Spine Surgery, 14482, Oberlinhaus, Potsdam, Germany
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RWTH Aachen University · Universitätsklinikum Aachen · Witten/Herdecke University
Affiliation as printed
Department of Arthroscopy and Joint Replacement, MVZ Praxisklinik Orthopädie Aachen, RWTH University Hospital Aachen, 52074, Aachen, Germany
Department of Medicine and Dentistry, University of Witten/Herdecke, 58455, Witten, Germany
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Queen Mary University of London · University of Salerno · Mile End Hospital · Keele University
Affiliation as printed
Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Mile End Hospital, London, E1 4DG, England
Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, 84081, Italy
School of Pharmacy and Bioengineering, Stoke on Trent, Keele University Faculty of Medicine, Keele, England
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