Editorial: Multi-omics data integration: key to thoroughly understanding the immune system

Frontiers in Cell and Developmental Biology, vol. 11, pp. 1207318

Abstract

The integration of platforms such as genomics, transcriptomics and proteomics has been acknowledged as a promising strategy for the in-depth characterization of complex cell systems and/or diseases. These omics platforms are now also helping us understand human immunity better. The immune system is a highly sophisticated network that maintains tissue homeostasis throughout the body. Thus, any disturbance in the immune system directly impacts diseases or indirectly drives malignant cell development. In this Research Topic, six manuscripts aim to describe the immune system by integrating different omics approaches, investigating the immunity functioning and its involvement in disease or the efficacy of therapeutical drug responses.

Authors 4

1. Cristina Jiménez

   Universidad de Salamanca · Instituto de Investigación Biomédica de Salamanca · Centro de Investigación Biomédica en Red de Cáncer · Instituto de Biología Molecular y Celular del Cáncer de Salamanca

   Affiliation as printed

   Hematology Department, University Hospital of Salamanca (HUS/IBSAL), CIBERONC and Cancer Research Institute of Salamanca-IBMCC (USAL-CSIC), Salamanca, Spain

2. María Hernández‐Sánchez

   Universidad Complutense de Madrid

   Affiliation as printed

   Department of Biochemistry and Molecular Biology, Universidad Complutense de Madrid, Madrid, Spain

3. Jacques J. M. van Dongen Aachen Department of Immunology, Leiden University Medical Center

   Consejo Superior de Investigaciones Científicas · Universidad de Salamanca · Leiden University Medical Center · Instituto de Investigación Biomédica de Salamanca · Centro de Investigación del Cáncer · Instituto de Biología Molecular y Celular del Cáncer de Salamanca

   Affiliation as printed

   Department of Immunology, Leiden University Medical Center (LUMC), Leiden, Netherlands

   Translational and Clinical Research Program, Cancer Research Center (IBMCC, University of Salamanca-CSIC), Cytometry Service, NUCLEUS, Department of Medicine, University of Salamanca and Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain

   Translational and Clinical Research Program, Cancer Research Center (IBMCC, University of Salamanca—CSIC), Cytometry Service, NUCLEUS, Department of Medicine, University of Salamanca and Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain

4. Paula Díez corresponding Aachen Department of Immunology, Leiden University Medical Center

   Leiden University Medical Center · Hospital Universitario Central de Asturias · Instituto de Investigación Sanitaria del Principado de Asturias

   Affiliation as printed

   Department of Immunology, Leiden University Medical Center (LUMC), Leiden, Netherlands

   Health Research Institute of Asturias (ISPA) and Asturias Central University Hospital (HUCA), Oviedo, Spain