Datasets for reporting of soft‐tissue sarcoma: recommendations from the International Collaboration on Cancer Reporting ( ICCR )

Histopathology, vol. 82, pp. 745–754

Abstract

AIMS: Soft-tissue tumours are rare and both accurate diagnosis and proper treatment represent a global challenge. Current treatment guidelines also recommend review by specialised pathologists. Here we report on international consensus-based datasets for the pathology reporting of biopsy and resection specimens of soft-tissue sarcomas. The datasets were produced under the auspices of the International Collaboration on Cancer Reporting (ICCR), a global alliance of international pathology and cancer organisations. METHODS AND RESULTS: According to the ICCR's guidelines for dataset development, an international expert panel consisting of pathologists, a surgical oncologist, and a medical oncologist produced a set of core and noncore data items for biopsy and resection specimens based on a critical review and discussion of current evidence. All professionals involved were subspecialised soft-tissue sarcoma experts and affiliated with tertiary referral centres. Commentary was provided for each data item to explain the rationale for selecting it as a core or noncore element, its clinical relevance, and to highlight potential areas of disagreement or lack of evidence, in which case a consensus position was formulated. Following international public consultation, the documents were finalised and ratified, and the datasets, which included a synoptic reporting guide, were published on the ICCR website. CONCLUSION: These first international datasets for soft-tissue sarcomas are aimed to promote high-quality, standardised pathology reporting. Their adoption will improve consistency of reporting, facilitate multidisciplinary communication, and enhance comparability of data, all of which will help to improve patient's management.

Authors 16

1. Angelo Paolo Dei Tos corresponding

   University of Padua · Azienda Ospedale - Università Padova

   Affiliation as printed

   Department of Medicine University of Padua School of Medicine Padua Italy

   Department of Pathology Azienda Ospedale‐Università Padova Padua Italy

   Department of Medicine, University of Padua School of Medicine, Padua, Italy

2. Fleur Webster
   Affiliation as printed

   International Collaboration on Cancer Reporting Sydney NSW Australia

   International Collaboration on Cancer Reporting, Sydney, NSW, Australia

3. Abbas Agaimy

   Friedrich-Alexander-Universität Erlangen-Nürnberg

   Affiliation as printed

   Institute of Pathology Friedrich‐Alexander‐Universität Erlangen‐Nürnberg Erlangen Bayern Germany

4. Judith V.M.G. Bovée Aachen Department of Pathology Leiden University Medical Center Leiden The Netherlands Department of Pathology, Leiden University Medical Center

   Leiden University Medical Center

   Affiliation as printed

   Department of Pathology Leiden University Medical Center Leiden the Netherlands

   Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands

5. Brendan Craig Dickson

   Mount Sinai Hospital · University of Toronto

   Affiliation as printed

   Department of Pathology & Laboratory Medicine, Mount Sinai Hospital and Department of Pathobiology & Laboratory Medicine University of Toronto Toronto ON Canada

   Department of Pathology & Laboratory Medicine, Mount Sinai Hospital and Department of Pathobiology & Laboratory Medicine University of Toronto Toronto ON Canada

6. Leona A. Doyle

   Brigham and Women's Hospital · Harvard University

   Affiliation as printed

   Department of Pathology, Brigham and Women's Hospital Harvard Medical School Boston MA USA

   Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA

7. Sarah Dry

   University of California, Los Angeles

   Affiliation as printed

   Department of Pathology University of California Los Angeles CA USA

   Department of Pathology, University of California, Los Angeles, CA, USA

8. Alessandro Gronchi

   Fondazione IRCCS Istituto Nazionale dei Tumori

   Affiliation as printed

   Department of Surgery Fondazione IRCCS Istituto Nazionale dei Tumori Milan Italy

   Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

9. Meera Hameed

   Memorial Sloan Kettering Cancer Center

   Affiliation as printed

   Department of Pathology and Laboratory Medicine Memorial Sloan Kettering Cancer Center New York NY USA

   Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

10. Chris Hemmings

    Canterbury Health Laboratories · University of Otago

    Affiliation as printed

    Department of Anatomic Pathology Canterbury Health Laboratories Christchurch New Zealand

    Department of Pathology and Biomedical Science University of Otago Medical School Christchurch New Zealand

    Department of Anatomic Pathology, Canterbury Health Laboratories, Christchurch, New Zealand

    Department of Pathology and Biomedical Science, University of Otago Medical School, Christchurch, New Zealand

11. Bernadette Liegl‐Atzwanger

    Medical University of Graz

    Affiliation as printed

    Diagnostic and Research Institute of Pathology, Comprehensive Cancer Centre Graz Medical University of Graz Graz Austria

    Diagnostic and Research Institute of Pathology, Comprehensive Cancer Centre Graz, Medical University of Graz, Graz, Austria

12. Khin Thway

    Royal Marsden NHS Foundation Trust · Institute of Cancer Research

    Affiliation as printed

    The Institute of Cancer Research London UK

    The Royal Marsden NHS Foundation Trust London UK

    The Institute of Cancer Research, London, UK

    The Royal Marsden NHS Foundation Trust, London, UK

13. Andrew J. Wagner

    Harvard University · Dana-Farber Cancer Institute

    Affiliation as printed

    Center for Sarcoma and Bone Oncology Dana‐Farber Cancer Institute Boston MA USA

    Harvard Medical School Boston MA USA

    Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Boston, MA, USA

    Harvard Medical School, Boston, MA, USA

14. Jian Wang

    Shanghai Medical College of Fudan University · Fudan University · Fudan University Shanghai Cancer Center

    Affiliation as printed

    Department of Oncology, Shanghai Medical College Fudan University Shanghai China

    Department of Pathology Fudan University Shanghai Cancer Center Shanghai China

    Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China

    Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China

15. Akihiko Yoshida

    National Cancer Centre Japan

    Affiliation as printed

    Department of Diagnostic Pathology National Cancer Center Hospital Tokyo Japan

    Rare Cancer Center National Cancer Center Hospital Tokyo Japan

    Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan

    Rare Cancer Center, National Cancer Center Hospital, Tokyo, Japan

16. Christopher D.�M. Fletcher

    Brigham and Women's Hospital · Harvard University

    Affiliation as printed

    Department of Pathology, Brigham and Women's Hospital Harvard Medical School Boston MA USA

    Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA