EANM practice guideline for quantitative SPECT-CT

European Journal of Nuclear Medicine and Molecular Imaging, vol. 50, pp. 980–995

Abstract

PURPOSE: Quantitative SPECT-CT is a modality of growing importance with initial developments in post radionuclide therapy dosimetry, and more recent expansion into bone, cardiac and brain imaging together with the concept of theranostics more generally. The aim of this document is to provide guidelines for nuclear medicine departments setting up and developing their quantitative SPECT-CT service with guidance on protocols, harmonisation and clinical use cases. METHODS: These practice guidelines were written by members of the European Association of Nuclear Medicine Physics, Dosimetry, Oncology and Bone committees representing the current major stakeholders in Quantitative SPECT-CT. The guidelines have also been reviewed and approved by all EANM committees and have been endorsed by the European Association of Nuclear Medicine. CONCLUSION: The present practice guidelines will help practitioners, scientists and researchers perform high-quality quantitative SPECT-CT and will provide a framework for the continuing development of quantitative SPECT-CT as an established modality.

Authors 9

1. John C. Dickson

   University College London Hospitals NHS Foundation Trust · University College London

   Affiliation as printed

   Institute of Nuclear Medicine, University College London Hospitals Foundation Trust, London, UK

2. Ian S. Armstrong

   Manchester University NHS Foundation Trust

   Affiliation as printed

   Nuclear Medicine, Manchester University NHS Foundation Trust, Manchester, UK

3. Pablo Mínguez Gabiña

   University of the Basque Country · BioCruces Health research Institute · Hospital de Cruces

   Affiliation as printed

   Department of Applied Physics, Faculty of Engineering, UPV/EHU, Bilbao, Spain

   Department of Medical Physics and Radiation Protection, Gurutzeta-Cruces University Hospital/Biocruces Health Research Institute, Barakaldo, Spain

4. Ana M. Denis-Bacelar

   National Physical Laboratory

   Affiliation as printed

   National Physical Laboratory, Teddington, UK

5. Aron K. Krizsan
   Affiliation as printed

   ScanoMed Nuclear Medicine Centers, Debrecen, Hungary

6. Jonathan I. Gear

   Royal Marsden NHS Foundation Trust · Institute of Cancer Research

   Affiliation as printed

   Joint Department of Physics Institute of Cancer Research and Royal Marsden, NHS Foundation Trust, Sutton, Surrey, UK

7. Tim VAN DEN WYNGAERT

   University of Antwerp · Antwerp University Hospital

   Affiliation as printed

   Department of Nuclear Medicine, Antwerp University Hospital, Edegem, Belgium

   Faculty of Medicine and Health Sciences (MICA - IPPON), , University of Antwerp, Wilrijk, Belgium

8. Lioe‐Fee de Geus‐Oei Aachen Department of Radiology Section of Nuclear Medicine

   Leiden University Medical Center · University of Twente

   Affiliation as printed

   Biomedical Photonic Imaging Group, University of Twente, Enschede, The Netherlands

   Department of Radiology, Section of Nuclear Medicine, Leiden University Medical Center, Leiden, The Netherlands

9. Ken Herrmann corresponding

   Essen University Hospital · University of Duisburg-Essen

   Affiliation as printed

   Department of Nuclear Medicine, University of Duisburg-Essen, and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany. Ken.Herrmann@uk-essen.de

   Department of Nuclear Medicine, University of Duisburg-Essen, and German Cancer Consortium (DKTK)-University Hospital Essen, Essen, Germany