Chiral Edge Current in Nematic Cell Monolayers

Physical Review X, vol. 12

Abstract

Cancerous human fibrosarcoma cells undergo collective migration at the edge of their colony by combining mesoscale self-organization and intrinsic handedness, showing how physical interactions alone can lead to biological functionality.

Authors 5

1. Victor Yashunsky

   Centre National de la Recherche Scientifique · Université Paris Sciences et Lettres · Sorbonne Université · Physique des Cellules et Cancers · Institut Curie

   Affiliation as printed

   Laboratoire Physico-Chimie Curie, Institut Curie, PSL Research University-Sorbonne Université, CNRS, 75005 Paris, France

2. Daniel J. Pearce

   University of Geneva · Massachusetts Institute of Technology

   Affiliation as printed

   Department of Biochemistry, University of Geneva, 1211 Geneva, Switzerland

   Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA

   Department of Physics, University of Geneva, 1211 Geneva, Switzerland

3. Carlès Blanch-Mercader

   University of Geneva

   Affiliation as printed

   Department of Biochemistry, University of Geneva, 1211 Geneva, Switzerland

   Department of Physics, University of Geneva, 1211 Geneva, Switzerland

4. Pascal Silberzan

   Centre National de la Recherche Scientifique · Université Paris Sciences et Lettres · Sorbonne Université · Physique des Cellules et Cancers · Institut Curie

   Affiliation as printed

   Laboratoire Physico-Chimie Curie, Institut Curie, PSL Research University-Sorbonne Université, CNRS, 75005 Paris, France

5. Luca Giomi Aachen Instituut-Lorentz

   Leiden University

   Affiliation as printed

   Instituut-Lorentz, Universiteit Leiden, P.O. Box 9506, 2300 RA Leiden, Netherlands