Negatively-charged supported lipid bilayers regulate neuronal adhesion and outgrowth

RSC Advances, vol. 12, pp. 30270–30277

Abstract

) groups. The synthesized SLBs were then tested as platforms for neuronal adhesion and network formation. Despite the expected repulsive electrostatic interactions, our work suggests that negatively charged SLBs may influence neurite elongation and branching, highlighting the potential of surface charge to tune neuronal processes at the neuron-SLB interface.

Authors 4

1. Chiara Ausilio

   Italian Institute of Technology

   Affiliation as printed

   Tissue Electronics, Istituto Italiano di Tecnologia, 80125 Napoli, Italy

2. Claudia Lubrano Aachen Faculty of Electrical Engineering and Information Technology

   Forschungszentrum Jülich · Italian Institute of Technology · University of Naples Federico II · RWTH Aachen University

   Affiliation as printed

   Dipartimento di Chimica, Materiali e Produzione Industriale, Università di Napoli Federico II, 80125, Naples, Italy

   Faculty of Electrical Engineering and Information Technology, RWTH Aachen, 52074, Germany

   Institute for Biological Information Processing-Bioelectronics, IBI-3, Forschungszentrum Juelich, 52428, Germany

   Tissue Electronics, Istituto Italiano di Tecnologia, 80125 Napoli, Italy

3. Anna Mariano

   Italian Institute of Technology

   Affiliation as printed

   Tissue Electronics, Istituto Italiano di Tecnologia, 80125 Napoli, Italy

4. Francesca Santoro corresponding Aachen Faculty of Electrical Engineering and Information Technology

   Forschungszentrum Jülich · Italian Institute of Technology · RWTH Aachen University

   Affiliation as printed

   Faculty of Electrical Engineering and Information Technology, RWTH Aachen, 52074, Germany

   Institute for Biological Information Processing-Bioelectronics, IBI-3, Forschungszentrum Juelich, 52428, Germany

   Tissue Electronics, Istituto Italiano di Tecnologia, 80125 Napoli, Italy