Decoding the transcriptome of calcified atherosclerotic plaque at single-cell resolution

• ChemR23 prevents phenotypic switching of vascular smooth muscle cells into macrophage-like foam cells in atherosclerosis

  2025 Cardiovascular Research article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access

  11

  citations
• Identification of a PRDM1-regulated T cell network to regulate atherosclerotic plaque inflammation

  2025 Genome Medicine article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access

  5

  citations
• NLRP3 Inflammasome Inhibition by the Novel Bispecific Antibody InflamAb Attenuates Atherosclerosis in Apolipoprotein E–Deficient Mice

  2025 JACC Basic to Translational Science article Biochemistry, Genetics and Molecular Biology Inflammasome and immune disorders Open access

  13

  citations
• Encompassing view of spatial and single-cell RNA sequencing renews the role of the microvasculature in human atherosclerosis

  2024 Nature Cardiovascular Research article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access

  67

  citations
• Genome-scale metabolic network of human carotid plaque reveals the pivotal role of glutamine/glutamate metabolism in macrophage modulating plaque inflammation and vulnerability

  2024 Cardiovascular Diabetology article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access

  20

  citations
• Human atherosclerotic plaque transcriptomics reveals endothelial beta-2 spectrin as a potential regulator a leaky plaque microvasculature phenotype

  2024 Angiogenesis article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access

  11

  citations
• Spatial multi-omics: novel tools to study the complexity of cardiovascular diseases

  2024 Genome Medicine article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  106

  citations
• Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification

  2023 Nature Genetics article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  123

  citations
• Tissue Inhibitor of Metalloproteinases-1 Interacts with CD74 to Promote AKT Signaling, Monocyte Recruitment Responses, and Vascular Smooth Muscle Cell Proliferation

  2023 Cells article Immunology and Microbiology Macrophage Migration Inhibitory Factor Open access

  15

  citations

9 results

• Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

  2020 Circulation Research article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access

  619

  citations

1 result