August 22, 2022 article Open access Orexin 2 receptor–selective agonist danavorexton improves narcolepsy phenotype in a mouse model and in human patients Proceedings of the National Academy of Sciences DOI: 10.1073/pnas.2207531119 Full text (OA) OpenAlex Authors 0 Author list not loaded yet. Cited by 8 stored of 94 Search Sort Most cited Newest Oldest Patent citations Title Any typearticle review book-chapter conference-paper preprint dissertation book dataset other Any fieldAgricultural and Biological Sciences Arts and Humanities Biochemistry, Genetics and Molecular Biology Business, Management and Accounting Chemical Engineering Chemistry Computer Science Decision Sciences Dentistry Earth and Planetary Sciences Economics, Econometrics and Finance Energy Engineering Environmental Science Health Professions Immunology and Microbiology Materials Science Mathematics Medicine Neuroscience Nursing Pharmacology, Toxicology and Pharmaceutics Physics and Astronomy Psychology Social Sciences Veterinary Open access Oveporexton for Narcolepsy Type 1 — Results from Two Phase 3 Trials 2026 New England Journal of Medicine article Neuroscience Sleep and Wakefulness Research Open access 2 citations Safety, tolerability, and efficacy of alixorexton, a selective orexin 2 receptor agonist for narcolepsy type 1 (Vibrance-1): a randomised, double-blind, placebo-controlled, phase 2 trial 2026 The Lancet Neurology article Neuroscience Sleep and Wakefulness Research 0 citations Effects of Oveporexton, an Orexin Receptor 2–Selective Agonist, on Cognition in Narcolepsy Type 1 2025 JAMA Neurology article Neuroscience Sleep and Wakefulness Research Open access 11 citations Oveporexton, an Oral Orexin Receptor 2–Selective Agonist, in Narcolepsy Type 1 2025 New England Journal of Medicine article Neuroscience Sleep and Wakefulness Research 63 citations TAK-925 (Danavorexton), an Orexin Receptor 2 Agonist, Reduces Opioid-induced Respiratory Depression and Sedation without Affecting Analgesia in Healthy Men 2025 Anesthesiology article Neuroscience Neuroscience of respiration and sleep Open access 14 citations Recent insights into the pathophysiology of narcolepsy type 1 2024 Sleep Medicine Reviews article Neuroscience Sleep and Wakefulness Research Open access 13 citations Narcolepsy Type 1: Should We Only Target Hypocretin Receptor 2? 2023 Clinical and Translational Neuroscience article Neuroscience Sleep and Wakefulness Research Open access 3 citations Activated Wake Systems in Narcolepsy Type 1 2023 Annals of Neurology article Neuroscience Sleep and Wakefulness Research Open access 18 citations 8 results References 3 Search Sort Most cited Newest Oldest Patent citations Title Any typearticle review book-chapter conference-paper preprint dissertation book dataset other Any fieldAgricultural and Biological Sciences Arts and Humanities Biochemistry, Genetics and Molecular Biology Business, Management and Accounting Chemical Engineering Chemistry Computer Science Decision Sciences Dentistry Earth and Planetary Sciences Economics, Econometrics and Finance Energy Engineering Environmental Science Health Professions Immunology and Microbiology Materials Science Mathematics Medicine Neuroscience Nursing Pharmacology, Toxicology and Pharmaceutics Physics and Astronomy Psychology Social Sciences Veterinary Open access European guideline and expert statements on the management of narcolepsy in adults and children 2021 European Journal of Neurology article Neuroscience Sleep and Wakefulness Research Open access 165 citations European guideline and expert statements on the management of narcolepsy in adults and children 2021 Journal of Sleep Research article Neuroscience Sleep and Wakefulness Research Open access 121 citations Intermediate hypocretin-1 cerebrospinal fluid levels and typical cataplexy: their significance in the diagnosis of narcolepsy type 1 2022 SLEEP article Neuroscience Sleep and Wakefulness Research Open access 34 citations 3 results