Towards a chip-based impedimetric biosensor for gaseous H202 detection

IEEE International Symposium on Olfaction and Electronic Nose (ISOEN), vol. 12, pp. 1–4

Abstract

This paper presents a novel approach for the detection of hydrogen peroxide (H2O2) vapor at low concentrations and room temperature conditions, as these are often used for sterilization in medical industry. Interdigitated electrode structures (IDEs) have been fabricated on glass substrates by means of microfabrication techniques and Ti/Pt evaporation. Impedance spectroscopy is used for impedance measurements of the IDE structures in H2O2atmosphere, which was provided by a glass bottle containing 20 mL of 35% w/w H2O2(i.e., free evaporation in a confined space with stable and homogenous temperature). The sensor signal shows changes by varying the H2O2concentrations inside the gas-tight glass bottle. Selectivity was achieved by means of the enzyme horse radish peroxidase. The detection of low concentrations of H2O2gas at room temperature and in the aerosol phase is performed in this study for the first time, which paves the path towards on-line monitoring of H2O2gas in aseptic processing.

Authors 5

1. Farnoosh Vahidpour Aachen Institute of Nano- und Biotechnologies Aachen University of Applied Sciences

   FH Aachen

   Affiliation as printed

   Institute of Nano- und Biotechnologies Aachen University of Applied Sciences,Jülich,Germany

2. Yousef Alghazali Aachen Institute of Nano- und Biotechnologies Aachen University of Applied Sciences

   FH Aachen

   Affiliation as printed

   Institute of Nano- und Biotechnologies Aachen University of Applied Sciences,Jülich,Germany

3. Steffen Thies
   Affiliation as printed

   SKAN AG,Allschwil,Germany

   SKAN AG, Allschwil, Germany

4. Gregor Hommes
   Affiliation as printed

   SKAN AG,Allschwil,Germany

   SKAN AG, Allschwil, Germany

5. Michael Josef Schöning Aachen Institute of Nano- und Biotechnologies Aachen University of Applied Sciences

   FH Aachen

   Affiliation as printed

   Institute of Nano- und Biotechnologies Aachen University of Applied Sciences,Jülich,Germany