Frontispiece: Release of Molecular Cargo from Polymer Systems by Mechanochemistry

Chemistry - A European Journal, vol. 28

Abstract

The incorporation of force-responsive groups, known as mechanophores, into macromolecular nanosystems has enabled access to previously unseen responsive behaviours as well as sophisticated functions of the resulting structures and advanced materials. The on-demand release or activation of compounds such as reaction catalysts, pharmaceutically active compounds, or monomers for self-healing of a material by an external trigger is a desired and important goal. In this review, we show how sonochemical activation by ultrasound (ultrasound-induced mechanochemistry) and the compression of bulk material can be used to create molecular cargo release systems from polymer-based architectures in solution. We also discuss important design concepts for these truly advanced materials, as well as their synthesis and applications. More information can be found in the Review article by B. M. Schmidt et al. (DOI: 10.1002/chem.202103860).

Authors 3

1. Robin Küng

   Heinrich Heine University Düsseldorf

   Affiliation as printed

   Institut für Organische Chemie und Makromolekulare Chemie Heinrich-Heine-Universität Düsseldorf Universitätsstraße 1 40225 Düsseldorf Germany

2. Robert Göstl Aachen

   DWI – Leibniz Institute for Interactive Materials

   Affiliation as printed

   DWI – Leibniz Institute for Interactive Materials Forckenbeckstr. 50 52056 Aachen Germany

3. Bernd M. Schmidt corresponding

   Heinrich Heine University Düsseldorf

   Affiliation as printed

   Institut für Organische Chemie und Makromolekulare Chemie Heinrich-Heine-Universität Düsseldorf Universitätsstraße 1 40225 Düsseldorf Germany