POS-550 MASS-SPECTROMETRIC IDENTIFICATION OF POST-TRANSLATIONAL GUANIDINYLATED YB-1 PROTEIN IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

Kidney International Reports, vol. 7, pp. S238

Abstract

With continuous identification of post-translational modified isoforms of proteins, it is becoming increasingly clear that post-translational modifications limit or modify the biological functions of native proteins are majorly involved in development of various chronic disease. This is mostly due to technically advanced molecular identification and quantification methods, mainly based on mass spectrometry. Mass spectrometry has become one of the most powerful tools for the identification of lipids.

Authors 4

1. Juliane Hermann Aachen Institute for Molecular Cardiovascular Research (IMCAR)

   RWTH Aachen University

   Affiliation as printed

   rwth, institute for molecular cardiovascular research, Aachen, Germany

2. Michaela Lellig Aachen Institute for Molecular Cardiovascular Research (IMCAR)

   RWTH Aachen University

   Affiliation as printed

   rwth, institute for molecular cardiovascular research, Aachen, Germany

3. Ute Raffetseder Aachen Nephrology and Clinical Immunology

   RWTH Aachen University

   Affiliation as printed

   rwth, Nephrology and Clinical Immunology, Aachen, Germany

4. Joachim Jankowski Aachen Institute for Molecular Cardiovascular Research (IMCAR)

   RWTH Aachen University

   Affiliation as printed

   rwth, Institute for molecular cardiovascular research, Aachen, Germany