CADASIL

• Heterogenous microglial reactivity contrasts with stable vascular transcriptional programs in mouse models of Alzheimer’s, CADASIL, and Traumatic Brain Injury

  2026 Nature Communications article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access

  0

  citations
• 3D Vessels-on-Chip using isogenic hiPSC-derived VSMCs reveal NOTCH3-driven alterations in brain small vessel disease

  2026 Stem Cell Reports article Medicine Cerebrovascular and genetic disorders Open access

  0

  citations
• Impairment of hippocampal gamma oscillations, mitochondria and neurovascular function in CADASIL

  2026 Brain article Medicine Cerebrovascular and genetic disorders Open access

  1

  citations
• Small Vessel Disease Phenotype Associated With Monoallelic NOTCH3 Loss-of-Function Variants

  2025 Neurology article Medicine Cerebrovascular and genetic disorders Open access

  4

  citations
• Disease Severity Staging System for NOTCH3 -Associated Small Vessel Disease, Including CADASIL

  2024 JAMA Neurology article Medicine Cerebrovascular and genetic disorders Open access

  24

  citations
• Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial

  2023 The Lancet Neurology article Medicine Cerebrovascular and genetic disorders Open access

  38

  citations
• Locus coeruleus pathology is associated with cerebral microangiopathy at autopsy

  2023 Alzheimer s & Dementia article Medicine Intracerebral and Subarachnoid Hemorrhage Research Open access

  9

  citations
• Three-tiered EGFr domain risk stratification for individualized NOTCH3-small vessel disease prediction

  2022 Brain article Medicine Cerebrovascular and genetic disorders Open access cited by 1 patent

  60

  citations
• Active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model

  2022 EMBO Molecular Medicine article Medicine Cerebrovascular and genetic disorders Open access

  29

  citations
• Effect of NOTCH3 EGFr Group, Sex, and Cardiovascular Risk Factors on CADASIL Clinical and Neuroimaging Outcomes

  2022 Stroke article Medicine Cerebrovascular and genetic disorders Open access

  42

  citations
• NOTCH3 active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model

  2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cerebrovascular and genetic disorders Open access

  0

  citations
• Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Family Members With a Pathogenic NOTCH3 Variant Can Have a Normal Brain Magnetic Resonance Imaging and Skin Biopsy Beyond Age 50 Years

  2022 Stroke article Medicine Cerebrovascular and genetic disorders Open access

  23

  citations
• Cognition, mood and behavior in CADASIL

  2022 Cerebral Circulation - Cognition and Behavior article Medicine Cerebrovascular and genetic disorders Open access

  24

  citations
• Hereditary Cerebral Small Vessel Diseases and Stroke: A Guide for Diagnosis and Management

  2021 Stroke article Medicine Cerebrovascular and genetic disorders Open access

  47

  citations
• Cysteine-Altering NOTCH3 Variants Are a Risk Factor for Stroke in the Elderly Population

  2020 Stroke article Medicine Cerebrovascular and genetic disorders Open access

  37

  citations
• Broad phenotype of cysteine-altering NOTCH3 variants in UK Biobank

  2020 Neurology article Medicine Cerebrovascular and genetic disorders Open access

  101

  citations
• Heritable and non-heritable uncommon causes of stroke

  2020 Journal of Neurology article Medicine Acute Ischemic Stroke Management Open access

  64

  citations
• Monogenic cerebral small‐vessel diseases: diagnosis and therapy. Consensus recommendations of the European Academy of Neurology

  2020 European Journal of Neurology article Medicine Cerebrovascular and genetic disorders Open access

  194

  citations

18 results