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Summary: international consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes

European Journal of Cardio-Thoracic Surgery, vol. 60, pp. 481–496

Abstract

This International evidence-based nomenclature and classification consensus on the congenital bicuspid aortic valve and its aortopathy recognizes 3 types of bicuspid aortic valve: 1. Fused type, with 3 phenotypes: right-left cusp fusion, right-non cusp fusion and left-non cusp fusion; 2. 2-sinus type with 2 phenotypes: Latero-lateral and antero-posterior; and 3. Partial-fusion or forme fruste. This consensus recognizes 3 bicuspid-aortopathy types: 1. Ascending phenotype; root phenotype; and 3. extended phenotypes.

Authors 51

  1. Héctor I. Michelena corresponding

    Mayo Clinic

    Affiliation as printed

    Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA

  2. University of Campania "Luigi Vanvitelli"

    Affiliation as printed

    Department of Translational Medical Sciences, University of Campania “L. Vanvitelli”, Naples, Italy

    Department of Translational Medical Sciences, University of Campania "L. Vanvitelli", Naples, Italy

  3. Vall d'Hebron Institut de Recerca

    Affiliation as printed

    Department of Cardiology, Hospital Vall d’Hebron, Vall d’Hebron Research Institute (VHIR) Ciber-CV, Barcelona, Spain

    Department of Cardiology, Hospital Vall d'Hebron, Vall d'Hebron Research Institute (VHIR) Ciber-CV, Barcelona, Spain

  4. Mayo Clinic

    Affiliation as printed

    Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA

    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA

  5. Mayo Clinic

    Affiliation as printed

    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA

  6. Weill Cornell Medicine

    Affiliation as printed

    Division of Cardiology, Weill Cornell Medicine, New York, NY, USA

  7. Weill Cornell Medicine

    Affiliation as printed

    Division of Cardiology, Weill Cornell Medicine, New York, NY, USA

  8. Instituto de Investigación Biomédica de Málaga · Universidad de Málaga

    Affiliation as printed

    ?>Departamento de Biología Animal, Facultad de Ciencias, Instituto de Investigación Biomédica de Málaga, Universidad de Málaga, Ciber-CV, Málaga, Spain

  9. MedStar Health Research Institute

    Affiliation as printed

    MedStar Health Research Institute, Washington, DC, USA

  10. Children's Hospital Colorado · University of Colorado Anschutz

    Affiliation as printed

    Department of Radiology, Children’s Hospital Colorado, University of Colorado, Anschutz Medical Campus, Colorado, USA

    Department of Radiology, Children's Hospital Colorado, University of Colorado, Anschutz Medical Campus, Colorado, USA

  11. Affiliation as printed

    ?>Cardiovascular Division, American British Cowdray Medical Center, Mexico City, Mexico

  12. Cliniques Universitaires Saint-Luc · UCLouvain

    Affiliation as printed

    ?>Division of Cardiothoracic and Vascular Surgery, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

  13. Stanford Medicine · Stanford University

    Affiliation as printed

    ?>Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Palo Alto, CA, USA

    Department of Pediatrics, Division of Pediatric Cardiology, Stanford University, Palo Alto, CA, USA

  14. University of Calgary · Libin Cardiovascular Institute of Alberta

    Affiliation as printed

    ?>Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada

  15. Universität Hamburg

    Affiliation as printed

    Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Hamburg, Germany

  16. Leiden University Medical Center

    Affiliation as printed

    Department of Cardiology, Leiden University Medical Center, Leiden, Netherlands

  17. The University of Texas Southwestern Medical Center

    Affiliation as printed

    Cardiothoracic Imaging Division, Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA

  18. Institute Mutualiste Montsouris

    Affiliation as printed

    Department of Cardiac Surgery, Institute Mutualiste Montsouris, Paris, France

  19. The University of Texas Health Science Center at Houston

    Affiliation as printed

    ?>Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA

  20. University of Leeds

    Affiliation as printed

    ?>Department of Biomedical Imaging Science, Leeds Institute to Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK

  21. Carol Davila University of Medicine and Pharmacy · Institutul de Urgenţă pentru Boli Cardiovasculare "Prof.Dr. C.C. Iliescu"

    Affiliation as printed

    ?>Department of Cardiology, University of Medicine and Pharmacy “Carol Davila”—Euroecolab, Emergency Institute for Cardiovascular Diseases “Prof. Dr. C. C. Iliescu”, Bucharest, Romania

  22. University of California, San Francisco

    Affiliation as printed

    Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA

  23. Instituto de Salud Carlos III · Centro de Investigación en Red en Enfermedades Cardiovasculares · Hospital Clínic de Barcelona · Consorci Institut D'Investigacions Biomediques August Pi I Sunyer · CERCA Institution · Universitat de Barcelona

    Affiliation as printed

    ?>Cardiovascular Institute, Hospital Clínic, Universitat de Barcelona, IDIBAPS; CIBERCV, ISCIII (CB16/11/00354); CERCA Programme

    CERCA Programme

  24. Affiliation as printed

    Department of Cardiovascular Surgery, Marcus Valve Center, Piedmont Heart Institute, Atlanta, GA, USA

  25. Institut universitaire de cardiologie et de pneumologie de Québec · Université Laval

    Affiliation as printed

    ?>Department of Cardiology, Québec Heart & Lung Institute, Laval University, Québec, Canada

  26. Mayo Clinic

    Affiliation as printed

    Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA

  27. University of Liège · Maria Cecilia Hospital · Centre Hospitalier Universitaire de Liège

    Affiliation as printed

    ?>Department of Cardiology, University of Liège Hospital, GIGA Cardiovascular Sciences, CHU Sart Tilman, Liège,Belgium

    ?>Gruppo Villa Maria Care and Research, Maria Cecilia Hospital, Cotignola, Italy

    Anthea Hospital, Bari, Italy

  28. Leipzig Heart Institute

    Affiliation as printed

    University Clinic of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany

  29. Yale New Haven Hospital · Yale University

    Affiliation as printed

    Yale University School of Medicine & Yale New Haven Hospital, New Haven, CT, USA

  30. University of British Columbia · St. Paul's Hospital

    Affiliation as printed

    St Paul's Hospital, University of British Columbia, Vancouver, Canada

  31. The University of Texas Health Science Center at Houston

    Affiliation as printed

    ?>Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA

  32. Yale New Haven Hospital · Yale University

    Affiliation as printed

    Yale University School of Medicine & Yale New Haven Hospital, New Haven, CT, USA

  33. University of British Columbia · St. Paul's Hospital

    Affiliation as printed

    St Paul's Hospital, University of British Columbia, Vancouver, Canada

  34. Boston Children's Hospital · Harvard University

    Affiliation as printed

    Cardiac Registry, Departments of Cardiology, Pathology and Cardiac Surgery, Boston Children’s Hospital, Boston, MA, USA

    Department of Pediatrics, Harvard Medical School, Boston, MA, USA

    Cardiac Registry, Departments of Cardiology, Pathology and Cardiac Surgery, Boston Children's Hospital, Boston, MA, USA

  35. Northwestern University

    Affiliation as printed

    Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA

  36. University of Pennsylvania Health System · University of Pennsylvania

    Affiliation as printed

    Cardiovascular Medicine Division, University of Pennsylvania Medical Center and Penn Cardiovascular Institute, Philadelphia, PA, USA

  37. Baylor University Medical Center · Texas A&M University

    Affiliation as printed

    Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, TX, USA

    Texas A & M School of Medicine, Dallas, TX, USA

  38. Asan Medical Center · University of Ulsan

    Affiliation as printed

    University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea

  39. St. Paul's Hospital

    Affiliation as printed

    Department of Radiology, St. Paul’s Hospital, Vancouver, BC, Canada

    Department of Radiology, St. Paul's Hospital, Vancouver, BC, Canada

  40. University of Maryland, Baltimore

    Affiliation as printed

    Department of Radiology, University of Maryland School of Medicine, Baltimore, MD, USA

  41. Western University

    Affiliation as printed

    Schulich School of Medicine and Dentistry, London, ON, Canada

  42. Cleveland Clinic

    Affiliation as printed

    Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH, USA

  43. Washington University in St. Louis

    Affiliation as printed

    Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA

  44. University of Pennsylvania

    Affiliation as printed

    Division of Cardiac Surgery, University of Pennsylvania, Philadelphia, PA, USA

  45. Massachusetts General Hospital

    Affiliation as printed

    Division of Cardiac Surgery, Massachusetts General Hospital, Boston, MA, USA

  46. Cliniques Universitaires Saint-Luc · UCLouvain

    Affiliation as printed

    ?>Division of Cardiothoracic and Vascular Surgery, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

  47. European Hospital

    Affiliation as printed

    Department of Cardiac Surgery, European Hospital and Unicamillus University, Rome, Italy

  48. Mayo Clinic

    Affiliation as printed

    Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA

  49. Leiden University Medical Center

    Affiliation as printed

    Department of Cardiology, Leiden University Medical Center, Leiden, Netherlands

  50. University of Washington

    Affiliation as printed

    Division of Cardiology, University of Washington, Seattle, WA, USA

  51. Universitätsklinikum des Saarlandes · Saarland University

    Affiliation as printed

    Division of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg, Saar, Germany

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References 53