Pulling the Strings of the Tumor Microenvironment

Cancer Immunology Research, vol. 10, pp. 4

Abstract

Macrophages are in the spotlight of cancer immunotherapy research because they exert a wide spectrum of protumorigenic functions. In this issue, Pfirschke and colleagues report that macrophage targeting pulls the strings of the tumor microenvironment, ultimately leading to a coordinated antitumorigenic immune reaction in a lung carcinoma mouse model.

Authors 2

1. Claudia Burrello corresponding

   The Netherlands Cancer Institute

   Affiliation as printed

   1Division of Tumor Biology and Immunology, Oncode Institute, Netherlands Cancer Institute, Amsterdam, the Netherlands

2. Karin E. de Visser Aachen 2Department of Immunology

   Leiden University · Leiden University Medical Center · The Netherlands Cancer Institute

   Affiliation as printed

   1Division of Tumor Biology and Immunology, Oncode Institute, Netherlands Cancer Institute, Amsterdam, the Netherlands

   2Department of Immunology, Leiden University Medical Centre, Leiden, the Netherlands