Multimodality imaging in patients with heart failure and preserved ejection fraction: an expert consensus document of the European Association of Cardiovascular Imaging
European Heart Journal - Cardiovascular Imaging, vol. 23, pp. e34–e61
Abstract
Nearly half of all patients with heart failure (HF) have a normal left ventricular (LV) ejection fraction (EF) and the condition is termed heart failure with preserved ejection fraction (HFpEF). It is assumed that in these patients HF is due primarily to LV diastolic dysfunction. The prognosis in HFpEF is almost as severe as in HF with reduced EF (HFrEF). In contrast to HFrEF where drugs and devices are proven to reduce mortality, in HFpEF there has been limited therapy available with documented effects on prognosis. This may reflect that HFpEF encompasses a wide range of different pathological processes, which multimodality imaging is well placed to differentiate. Progress in developing therapies for HFpEF has been hampered by a lack of uniform diagnostic criteria. The present expert consensus document from the European Association of Cardiovascular Imaging (EACVI) provides recommendations regarding how to determine elevated LV filling pressure in the setting of suspected HFpEF and how to use multimodality imaging to determine specific aetiologies in patients with HFpEF.
Authors 29
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Otto Armin Smiseth corresponding
Oslo University Hospital · University of Oslo
Affiliation as printed
Department of Cardiology, Oslo University Hospital, Rikshospitalet , Sognsvannsveien 20, Oslo,
Institute for Surgical Research, Oslo University Hospital, Rikshospitalet , Sognsvannsveien 20, Oslo,
Institute of Clinical Medicine, University of Oslo , Oslo,
Department of Cardiology, Oslo University Hospital, Rikshospitalet, Sognsvannsveien 20, Oslo, Norway
Institute for Surgical Research, Oslo University Hospital, Rikshospitalet, Sognsvannsveien 20, Oslo, Norway
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
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Charité - Universitätsmedizin Berlin
Affiliation as printed
Department of Internal Medicine and Cardiology, Campus Virchow Klinikum, Charité Universitätsmedizin Berlin , Berlin,
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Affiliation as printed
Cardiology Department, Hospital da Luz , Av. Lusíada, N° 100, Lisbon,
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University Hospital Centre Zagreb · University of Zagreb
Affiliation as printed
Department of Cardiovascular Diseases, University of Zagreb School of Medicine and University Hospital Center Zagreb , Zagreb,
Department of Cardiovascular Diseases, University of Zagreb School of Medicine and University Hospital Center Zagreb, Zagreb, Croatia
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Leiden University · Leiden University Medical Center
Affiliation as printed
Department of Cardiology, Leiden University Medical Centre , Albinusdreef 2, Leiden 2300 RC,
Department of Cardiology, Leiden University Medical Centre, Albinusdreef 2, Leiden 2300 RC, The Netherlands
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Laboratoire Traitement du Signal et de l'Image · CIC Rennes · Centre Hospitalier Universitaire de Rennes · Université Rennes 1 · Université de Rennes
Affiliation as printed
Service de Cardiologie Et Maladies Vasculaires Et CIC-IT 1414, CHU Rennes , 35000 Rennes,
Université de Rennes 1, LTSI , 35000 Rennes,
Service de Cardiologie Et Maladies Vasculaires Et CIC-IT 1414, CHU Rennes, 35000 Rennes, France
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Affiliation as printed
Department of Medical Sciences, Clinical Physiology and Cardiology, Uppsala University Hospital , Uppsala,
Department of Medical Sciences, Clinical Physiology and Cardiology, Uppsala University Hospital, Uppsala, Sweden
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Federico II University Hospital · University of Naples Federico II
Affiliation as printed
Department of Advanced Biomedical Sciences, Federico II University , Naples,
Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
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Cliniques Universitaires Saint-Luc · UCLouvain
Affiliation as printed
Division of Cardiology, Department of Cardiovascular Diseases, Cliniques Universitaires St. Luc, Pôle de Recherche Cardiovasculaire (CARD), Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain , Av Hippocrate, 10/2806 Brussels,
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Fondazione Toscana Gabriele Monasterio
Affiliation as printed
Fondazione Toscana Gabriele Monasterio , Via Moruzzi, 1, Pisa 56124,
Fondazione Toscana Gabriele Monasterio, Via Moruzzi, 1, Pisa 56124, Italy
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Affiliation as printed
Section of Cardiovascular Imaging, Heart and Vascular Institute, Cleveland Clinic , Cleveland, OH,
Section of Cardiovascular Imaging, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA
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University of Turku · Turku University Hospital · Turku PET Centre
Affiliation as printed
Turku PET Centre, University of Turku, and Turku University Hospital , Turku,
Turku PET Centre, University of Turku, and Turku University Hospital, Turku, Finland
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University of Liège · Maria Cecilia Hospital · Centre Hospitalier Universitaire de Liège
Affiliation as printed
Department of Cardiology, University of Liège Hospital, Domaine Universitaire du Sart Tilman , Liège B4000,
Gruppo Villa Maria Care and Research, Maria Cecilia Hospital, Cotignola, and Anthea Hospital , Bari,
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Universitätsklinikum St. Pölten · Karl Landsteiner University of Health Sciences
Affiliation as printed
Department of Internal Medicine 3, Karl Landsteiner University of Health Sciences, University Hospital St. Pölten , Krems,
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University Hospital Centre Zagreb · University of Zagreb
Affiliation as printed
Department of Cardiovascular Diseases, University of Zagreb School of Medicine and University Hospital Center Zagreb , Zagreb,
Department of Cardiovascular Diseases, University of Zagreb School of Medicine and University Hospital Center Zagreb, Zagreb, Croatia
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University of Belgrade · Univerzitetski Klinički Centar Srbije
Affiliation as printed
Department of Cardiology, Clinical Center of Serbia , Belgrade,
Faculty of Medicine, University of Belgrade , Belgrade,
Department of Cardiology, Clinical Center of Serbia, Belgrade, Serbia
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Affiliation as printed
Division of Cardiovascular Medicine, Brigham and Women's Hospital , Boston, MA,
Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA
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Oslo University Hospital · University of Oslo
Affiliation as printed
Department of Cardiology, Oslo University Hospital, Rikshospitalet , Sognsvannsveien 20, Oslo,
Institute for Surgical Research, Oslo University Hospital, Rikshospitalet , Sognsvannsveien 20, Oslo,
Institute of Clinical Medicine, University of Oslo , Oslo,
Department of Cardiology, Oslo University Hospital, Rikshospitalet, Sognsvannsveien 20, Oslo, Norway
Institute for Surgical Research, Oslo University Hospital, Rikshospitalet, Sognsvannsveien 20, Oslo, Norway
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
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Bogdan Alexandru Popescu corresponding
Carol Davila University of Medicine and Pharmacy · Institutul de Urgenţă pentru Boli Cardiovasculare "Prof.Dr. C.C. Iliescu"
Affiliation as printed
Department of Cardiology, University of Medicine and Pharmacy “Carol Davila”, Euroecolab, Emergency Institute for Cardiovascular Diseases “Prof. Dr. C. C. Iliescu” , Sos. Fundeni 258, sector 2, 022328 Bucharest,
Department of Cardiology, University of Medicine and Pharmacy "Carol Davila", Euroecolab, Emergency Institute for Cardiovascular Diseases "Prof. Dr. C. C. Iliescu", Sos. Fundeni 258, sector 2, 022328 Bucharest, Romania
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Affiliation as printed
Rikshospitalet , Sognsvannsveien 20 , Oslo , Norway;
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Carol Davila University of Medicine and Pharmacy
Affiliation as printed
Department of Cardiology , University of Medicine and Pharmacy "Carol Davila" , Euroecolab , Emergency Institute for Cardiovascular Diseases "Prof. Dr. C. C. Iliescu" , Sos. Fundeni 258 , sector 2 , 022328 Bucharest , Romania
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Carol Davila University of Medicine and Pharmacy
Affiliation as printed
Department of Cardiology , University of Medicine and Pharmacy "Carol Davila" , Euroecolab , Emergency Institute for Cardiovascular Diseases "Prof. Dr. C. C. Iliescu" , Sos. Fundeni 258 , sector 2 , 022328 Bucharest , Romania
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Affiliation as printed
Rikshospitalet , Sognsvannsveien 20 , Oslo , Norway;
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University of Turku · Carol Davila University of Medicine and Pharmacy · Turku University Hospital · Turku PET Centre
Affiliation as printed
Department of Cardiology , University of Medicine and Pharmacy "Carol Davila" , Euroecolab , Emergency Institute for Cardiovascular Diseases "Prof. Dr. C. C. Iliescu" , Sos. Fundeni 258 , sector 2 , 022328 Bucharest , Romania
Turku PET Centre, University of Turku, and Turku University Hospital, Turku, Finland
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Affiliation as printed
Rikshospitalet , Sognsvannsveien 20 , Oslo , Norway;
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Oslo University Hospital · University of Liège · University of Belgrade
Affiliation as printed
Domaine Universitaire du Sart Tilman , Lie `ge B4000 , Belgium;
Rikshospitalet , Sognsvannsveien 20 , Oslo , Norway;
Faculty of Medicine, University of Belgrade, Belgrade, Serbia;
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Oslo University Hospital · University of Belgrade
Affiliation as printed
Rikshospitalet , Sognsvannsveien 20 , Oslo , Norway;
Faculty of Medicine, University of Belgrade, Belgrade, Serbia;
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Oslo University Hospital · Carol Davila University of Medicine and Pharmacy · University of Belgrade · Institutul de Urgenţă pentru Boli Cardiovasculare "Prof.Dr. C.C. Iliescu"
Affiliation as printed
Rikshospitalet , Sognsvannsveien 20 , Oslo , Norway;
Department of Cardiology, University of Medicine and Pharmacy "Carol Davila", Euroecolab, Emergency Institute for Cardiovascular Diseases "Prof. Dr. C. C. Iliescu", Sos. Fundeni 258, sector 2, 022328 Bucharest, Romania
Faculty of Medicine, University of Belgrade, Belgrade, Serbia;
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