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Self-reported work productivity in people with multiple sclerosis and its association with mental and physical health

Disability and Rehabilitation, vol. 44, pp. 7096–7105

Abstract

Purpose This study aimed to identify mental health, physical health, demographic and disease characteristics relating to work productivity in people with multiple sclerosis (MS).Methods In this cross-sectional study, 236 employed people with MS (median age = 42 years, 78.8% female) underwent neurological and neuropsychological assessments. Additionally, they completed questionnaires inquiring about work productivity (presenteeism: reduced productivity while working, and absenteeism: loss of productivity due to absence from work), mental and physical health, demographic and disease characteristics. Multiple linear and logistic regression analyses were performed with presenteeism and absenteeism as dependent variables, respectively.Results A model with mental and physical health factors significantly predicted presenteeism F(11,202) = 11.33, p < 0.001, R2 = 0.38; a higher cognitive (p < 0.001) and physical impact (p = 0.042) of fatigue were associated with more presenteeism. A model with only mental health factors significantly predicted absenteeism; χ2(11)=37.72, p < 0.001, with R2 = 0.27 (Nagelkerke) and R2 = 0.16 (Cox and Snell). Specifically, we observed that more symptoms of depression (p = 0.041) and a higher cognitive impact of fatigue (p = 0.011) were significantly associated with more absenteeism.Conclusions In people with MS, both cognitive and physical impact of fatigue are positively related to presenteeism, while symptoms of depression and cognitive impact of fatigue are positively related to absenteeism.Implications for rehabilitationMultiple sclerosis (MS) affects people of working age, significantly interfering with work productivity.Higher cognitive and physical impact of fatigue were associated with more presenteeism in workers with MS.A higher cognitive impact of fatigue and more depressive symptoms were associated with absenteeism in workers with MS.Occupational and healthcare professionals should be aware of the impact of both physical and mental health on work productivity in workers with MS.

Authors 16

  1. Leiden University · University of Humanistic Studies · Elisabeth-TweeSteden Ziekenhuis

    Affiliation as printed

    Department of Care Ethics, University of Humanistic Studies, Utrecht, The Netherlands

    Department of Neurology, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands

    Institute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, The Netherlands

    National Multiple Sclerosis Foundation, Rotterdam, The Netherlands

  2. University of Humanistic Studies

    Affiliation as printed

    Department of Care Ethics, University of Humanistic Studies, Utrecht, The Netherlands

  3. University Medical Center Groningen · University of Groningen · MS4 Research Institute

    Affiliation as printed

    Department of Community & Occupational Medicine, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands

    MS4 Research Institute, Nijmegen, The Netherlands

  4. Tilburg University · North-West University

    Affiliation as printed

    Optentia, North West University of South Africa, Vanderbijlpark, South Africa

    Tilburg School of Social and Behavioural Sciences, Tranzo Scientific Centre for Care and Welfare, Tilburg University, Tilburg, The Netherlands

  5. University Medical Center Groningen · University of Groningen

    Affiliation as printed

    Department of Rehabilitation Medicine, Centre for Rehabilitation, University of Groningen, University Medical Centre Groningen, Haren, The Netherlands

  6. Elisabeth-TweeSteden Ziekenhuis

    Affiliation as printed

    Department of Neurology, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands

  7. Medisch Centrum Leeuwarden

    Affiliation as printed

    Department of Neurology, Medical Centre Leeuwarden, Leeuwarden, The Netherlands

  8. Jeroen Bosch Ziekenhuis

    Affiliation as printed

    Department of Neurology, Jeroen Bosch Hospital, ‘S-Hertogenbosch, The Netherlands

    Department of Neurology, Jeroen Bosch Hospital, 'S-Hertogenbosch, The Netherlands

  9. St. Antonius Ziekenhuis

    Affiliation as printed

    Department of Neurology, St. Antonius Hospital, Nieuwegein, The Netherlands

  10. Zuyderland Medisch Centrum

    Affiliation as printed

    Department of Neurology, Zuyderland Medical Centre, Sittard-Geleen, The Netherlands

  11. Catharina Ziekenhuis

    Affiliation as printed

    Department of Neurology, Catharina Hospital, Eindhoven, The Netherlands

  12. Maasstad Ziekenhuis

    Affiliation as printed

    Department of Neurology, Maasstad Hospital, Rotterdam, The Netherlands

  13. Canisius-Wilhelmina Ziekenhuis

    Affiliation as printed

    Department of Neurology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands

  14. Leiden University · Leiden University Medical Center

    Affiliation as printed

    Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands

    Institute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, The Netherlands

  15. University of Humanistic Studies · Elisabeth-TweeSteden Ziekenhuis

    Affiliation as printed

    Department of Care Ethics, University of Humanistic Studies, Utrecht, The Netherlands

    Department of Neurology, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands

  16. Leiden University

    Affiliation as printed

    Institute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, The Netherlands

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References 48