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Authors’ reply re: Universal screening versus risk-based protocols for antibiotic prophylaxis during childbirth to prevent early-onset Group B streptococcal disease: A systematic review and meta-analysis. (Response to BJOG-20-0671)

Abstract

Dear Editor, We would like to thank Dr. Lamont and colleagues for their interesting commentary.1 The authors point out very pressing topics that deserve more attention than we could provide in the original manuscript.They expressed concerns in their letter towards the heterogeneity of the data that were used in our meta-analysis. If incidences differ between regions and populations, absolute numbers on colonisation and neonatal infections might not be comparable. However, new policies were implemented in various settings, where differences in outcomes were measured under the same local circumstances. So as rightly mentioned by Lamont et al, data from the US cannot and should not be used as a blueprint for other parts of the world.1 Yet the general trend in developed countries that we observed, might shed some new light on the respective effectiveness of the strategies currently available.

Authors 5

  1. Geke Hasperhoven corresponding

    Maastricht University Medical Centre

    Affiliation as printed

    Maastricht University Medical Centre+

  2. Maastricht University Medical Centre

    Affiliation as printed

    Maastricht UMC

  3. Leiden University Medical Center

    Affiliation as printed

    Leiden University Medical Center

    Leiden University Medical Center May 6, 2020

  4. Maastricht University Medical Centre

    Affiliation as printed

    Maastricht University Medical Centre+

  5. Maastricht University Medical Centre

    Affiliation as printed

    Maastricht University Medical Centre+

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