Neonatal stroke in premature neonates

Seminars in Perinatology, vol. 45, pp. 151471

Abstract

There are many neuro-imaging studies on the presence of brain lesions in the preterm infant, using cranial ultrasound (cUS) and/or term equivalent age MRI (TEA-MRI). These studies however tend to focus on germinal matrix-intraventricular hemorrhage (GMH-IVH) and white matter injury. Data about perinatal arterial ischemic stroke (PAIS) or cerebral sinovenous thrombosis (CSVT) in the preterm infant are very limited. In fact, several large cohort studies on neuro-imaging in preterm infants do not even mention neonatal stroke.1, 2, 3, 4 Most studies about PAIS exclude preterm infants.5 The aim of this review was to provide an update on neonatal stroke in the preterm infant, with a focus on neuro-imaging findings.

Authors 2

1. Sylke Jeanne Steggerda Aachen Department of Neonatology, Leiden University Medical Center

   Leiden University Medical Center

   Affiliation as printed

   Department of Neonatology, Leiden University Medical Center, PO Box 85090, Utrecht 3508 AB, the Netherlands

2. Linda S. de Vries corresponding Aachen Department of Neonatology, Leiden University Medical Center

   University Medical Center Utrecht · Utrecht University · Leiden University Medical Center

   Affiliation as printed

   Department of Neonatology, Leiden University Medical Center, PO Box 85090, Utrecht 3508 AB, the Netherlands; Department of Neonatology, University Medical Center Utrecht, Utrecht University, the Netherlands. Electronic address: L.S.de_Vries@lumc.nl

   Department of Neonatology, Leiden University Medical Center, PO Box 85090, Utrecht 3508 AB, the Netherlands

   Department of Neonatology, University Medical Center Utrecht, Utrecht University, the Netherlands