Human Lung Slices: New Uses for an Old Model

• Ex vivo precision-cut liver slices model disease phenotype and monitor therapeutic response for liver monogenic diseases

  2024 F1000Research article Biochemistry, Genetics and Molecular Biology Metabolism and Genetic Disorders Open access

  6

  citations
• Ex vivo precision-cut liver slices model disease phenotype and monitor therapeutic response for liver monogenic diseases

  2023 F1000Research article Biochemistry, Genetics and Molecular Biology Metabolism and Genetic Disorders Open access

  5

  citations
• Ex vivo primary liver sections recapitulate disease phenotype and therapeutic rescue for liver monogenic diseases

  2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver physiology and pathology Open access

  1

  citations
• Post-COVID Syndrome: The Research Progress in the Treatment of Pulmonary sequelae after COVID-19 Infection

  2022 Pharmaceutics article Medicine Long-Term Effects of COVID-19 Open access

  21

  citations

4 results

• A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

  2020 Nature article Medicine SARS-CoV-2 and COVID-19 Research Open access

  691

  citations
• The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease

  2019 American Journal of Respiratory Cell and Molecular Biology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  271

  citations
• Building and Regenerating the Lung Cell by Cell

  2018 Physiological Reviews review Medicine Neonatal Respiratory Health Research Open access

  219

  citations
• A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED

  2016 American Journal of Respiratory and Critical Care Medicine article Medicine Asthma and respiratory diseases Open access

  213

  citations
• Use of precision cut lung slices as a translational model for the study of lung biology

  2019 Respiratory Research article Medicine Transplantation: Methods and Outcomes Open access

  210

  citations
• A Dynamic Bronchial Airway Gene Expression Signature of Chronic Obstructive Pulmonary Disease and Lung Function Impairment

  2013 American Journal of Respiratory and Critical Care Medicine article Medicine Chronic Obstructive Pulmonary Disease (COPD) Research Open access

  164

  citations
• COPD Readmissions

  2016 CHEST Journal article Medicine Chronic Obstructive Pulmonary Disease (COPD) Research Open access

  151

  citations
• Respiratory viral infection: a potential “missing link” in the pathogenesis of COPD

  2019 European Respiratory Review article Medicine Chronic Obstructive Pulmonary Disease (COPD) Research Open access

  149

  citations
• The early allergic response in small airways of human precision-cut lung slices

  2003 European Respiratory Journal article Medicine Asthma and respiratory diseases Open access

  145

  citations
• Defining critical roles for NF‐κB p65 and type I interferon in innate immunity to rhinovirus

  2012 EMBO Molecular Medicine article Immunology and Microbiology interferon and immune responses Open access

  82

  citations
• Differential Sensitivity of Differentiated Epithelial Cells to Respiratory Viruses Reveals Different Viral Strategies of Host Infection

  2008 Journal of Virology article Medicine Respiratory viral infections research Open access

  78

  citations
• Rhinovirus and asthma: Challenges and opportunities

  2020 Reviews in Medical Virology article Medicine Respiratory viral infections research Open access

  74

  citations
• Neurally Mediated Airway Constriction in Human and Other Species: A Comparative Study Using Precision-Cut Lung Slices (PCLS)

  2012 PLoS ONE article Medicine Asthma and respiratory diseases Open access

  68

  citations
• Rhinovirus-Induced Human Lung Tissue Responses Mimic Chronic Obstructive Pulmonary Disease and Asthma Gene Signatures

  2021 American Journal of Respiratory Cell and Molecular Biology article Medicine Chronic Obstructive Pulmonary Disease (COPD) Research Open access

  25

  citations
• Rupintrivir reduces RV-induced TH-2 cytokine IL-4 in precision-cut lung slices (PCLS) of HDM-sensitized mice ex vivo

  2019 Respiratory Research article Medicine Asthma and respiratory diseases Open access

  18

  citations

15 results