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Initial Experience With the Trevo NXT Stent Retriever

Frontiers in Neurology, vol. 12, pp. 704329

Abstract

Background: The application of a new coating to the delivery wire of the Trevo retriever has the potential to improve its handling. We therefore report our initial experience with this new stent retriever for mechanical thrombectomy of large and medium vessel occlusions. Methods: We pooled data of four high-volume European stroke centers over the time period from October 2020 to February 2021. Patients were included in our study if the Trevo NXT stent retriever was used as a first-line device. Primary endpoints were first-pass near-complete or complete reperfusion, defined as mTICI score of ≥2c. Secondary endpoints were final reperfusion, National Institutes of Health Stroke Scale (NIHSS) at 24 h and discharge, device malfunctions, complications during the procedure, and subjective ratings of the interventionalists regarding device functionality. Results: Eighty patients (39 women, mean age 74 ± 14 years) were eligible for our study. Median NIHSS at admission was 15 (IQR, 8–19), and median Alberta Stroke Program Early CT Score at baseline was 9 (IQR, 8–10). In 74 (93%) patients a primary combined approach was used as first-line technique. First-pass near-complete reperfusion was achieved in 43 (54%) and first-pass complete reperfusion in 34 (43%) patients. Final near-complete reperfusion was achieved in 66 (83%) patients after a median of 1.5 (1–3) passes, while final successful reperfusion was observed in 96% of our cases. We observed no device malfunctions. Median NIHSS at discharge was 2 (IQR, 0–5), and 3 patients (4%) suffered a symptomatic intracranial hemorrhage. Conclusions: Based on our initial data, we conclude that the Trevo NXT is an effective and safe tool for mechanical thrombectomy especially when used for combined approaches.

Authors 14

  1. University Hospital of Basel

    Affiliation as printed

    Department of Neuroradiology, Clinic for Radiology and Nuclear Medicine, University Hospital Basel, Basel, Switzerland

  2. University Hospital Heidelberg

    Affiliation as printed

    Department of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany

  3. University Hospital Heidelberg

    Affiliation as printed

    Department of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany

  4. Hospital Clínico San Carlos

    Affiliation as printed

    Department of Neuroradiology, Hospital Clínico San Carlos, Madrid, Spain

  5. Hospital Clínico San Carlos

    Affiliation as printed

    Department of Neuroradiology, Hospital Clínico San Carlos, Madrid, Spain

  6. Azienda Ospedaliero-Universitaria Careggi

    Affiliation as printed

    Neurovascular Interventional Unit, Careggi University Hospital, Florence, Italy

  7. Universitätsklinikum Aachen · RWTH Aachen University

    Affiliation as printed

    Department of Neuroradiology, University Hospital RWTH Aachen, Aachen, Germany

  8. Universitätsklinikum Aachen · RWTH Aachen University

    Affiliation as printed

    Department of Neuroradiology, University Hospital RWTH Aachen, Aachen, Germany

  9. University Hospital of Basel

    Affiliation as printed

    Department of Neuroradiology, Clinic for Radiology and Nuclear Medicine, University Hospital Basel, Basel, Switzerland

  10. University Hospital of Basel

    Affiliation as printed

    Department of Neuroradiology, Clinic for Radiology and Nuclear Medicine, University Hospital Basel, Basel, Switzerland

  11. University Hospital of Basel

    Affiliation as printed

    Department of Neuroradiology, Clinic for Radiology and Nuclear Medicine, University Hospital Basel, Basel, Switzerland

  12. University Hospital of Basel

    Affiliation as printed

    Department of Neuroradiology, Clinic for Radiology and Nuclear Medicine, University Hospital Basel, Basel, Switzerland

  13. University Hospital of Basel

    Affiliation as printed

    Department of Neuroradiology, Clinic for Radiology and Nuclear Medicine, University Hospital Basel, Basel, Switzerland

  14. University Hospital of Basel

    Affiliation as printed

    Department of Neuroradiology, Clinic for Radiology and Nuclear Medicine, University Hospital Basel, Basel, Switzerland

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References 27