Deep Dive into Atrial Functional Mitral Regurgitation

Structural Heart, vol. 5, pp. 508–509

Abstract

Atrial functional mitral regurgitation (AFMR) has been recently recognized as a subcategory of functional mitral regurgitation characterized by severe left atrial (LA) dilation and normal left ventricular (LV) dimensions and function. AFMR typically occurs in patients with atrial fibrillation (AF) and/or heart failure with preserved ejection fraction.1 Mitral annular dilation caused by severe LA remodeling has been traditionally considered the key mechanism of AFMR.1 However, the use of 3-dimensional imaging techniques and the study of LA mechanics have shown that other factors such as insufficient leaflet remodeling, atriogenic leaflet tethering, impaired annular dynamics and altered atrial mechanics may contribute to AFMR pathogenesis.

Authors 2

1. Maria Chiara Meucci Aachen Department of Cardiology, Leiden University Medical Center

   Leiden University Medical Center · Agostino Gemelli University Polyclinic · Università Cattolica del Sacro Cuore

   Affiliation as printed

   Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands

   Department of Cardiovascular and Thoracic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy

2. Victoria Delgado corresponding Aachen Department of Cardiology, Leiden University Medical Center

   Leiden University Medical Center

   Affiliation as printed

   Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands