CD8+ T cell differentiation and dysfunction in cancer

• Defining nature, responses and drivers of regulatory- and conventional CD4+ T cells in the human term decidua

  2026 Frontiers in Immunology article Immunology and Microbiology Reproductive System and Pregnancy Open access

  0

  citations
• Efficient generation of human cDC1-like cells to detect and enhance tumor-reactive T cells via CD4+ T cell help

  2026 Cell Reports Methods article Immunology and Microbiology Immunotherapy and Immune Responses Open access

  0

  citations
• Stem-like PD-1 + TCF-1 + CD8 + T cells result from helpless priming and rely on CD4 + T-cell help to complete their cytotoxic effector differentiation

  2026 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology T-cell and B-cell Immunology Open access

  2

  citations
• Immunological features of clear-cell renal-cell carcinoma and resistance to immune checkpoint inhibitors

  2025 Nature Reviews Nephrology review Medicine Cancer Immunotherapy and Biomarkers

  40

  citations
• Intratumoral gene delivery of 4-1BBL boosts IL-12-triggered anti-glioblastoma immunity

  2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Glioma Diagnosis and Treatment Open access

  0

  citations
• The importance of type I interferon in orchestrating the cytotoxic T-cell response to cancer

  2024 Immunology Letters article Immunology and Microbiology Immunotherapy and Immune Responses Open access

  19

  citations
• A multidimensional analysis reveals distinct immune phenotypes and the composition of immune aggregates in pediatric acute myeloid leukemia

  2024 Leukemia article Medicine Acute Myeloid Leukemia Research Open access

  20

  citations
• PD-1 or CTLA-4 blockade promotes CD86-driven Treg responses upon radiotherapy of lymphocyte-depleted cancer in mice

  2024 Journal of Clinical Investigation article Medicine Cancer Immunotherapy and Biomarkers Open access

  36

  citations
• Multiomics and spatial mapping characterizes human CD8 + T cell states in cancer

  2023 Science Translational Medicine article Medicine Cancer Immunotherapy and Biomarkers Open access

  94

  citations
• A multidimensional analysis reveals distinct immune phenotypes and the composition of immune aggregates in pediatric acute myeloid leukemia

  2023 medRxiv preprint Medicine Acute Myeloid Leukemia Research Open access

  8

  citations
• The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth

  2023 Cancer Cell article Medicine Cancer Cells and Metastasis Open access cited by 3 patents

  3,982

  citations
• CD103 and CD39 coexpression identifies neoantigen-specific cytotoxic T cells in colorectal cancers with low mutation burden

  2023 Journal for ImmunoTherapy of Cancer article Medicine Cancer Immunotherapy and Biomarkers Open access

  29

  citations

12 results

• The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes

  2020 Cancer Cell article Medicine Cancer Immunotherapy and Biomarkers Open access cited by 3 patents

  720

  citations

1 result