National Protocol for Model-Based Selection for Proton Therapy in Head and Neck Cancer
International Journal of Particle Therapy, vol. 8, pp. 354–365
Abstract
In the Netherlands, the model-based approach is used to identify patients with head and neck cancer who may benefit most from proton therapy in terms of prevention of late radiation-induced side effects in comparison with photon therapy. To this purpose, a National Indication Protocol Proton therapy for Head and Neck Cancer patients (NIPP-HNC) was developed, which has been approved by the health care authorities. When patients qualify according to the guidelines of the NIPP-HNC, proton therapy is fully reimbursed. This article describes the procedures that were followed to develop this NIPP-HNC and provides all necessary information to introduce model-based selection for patients with head and neck cancer into routine clinical practice.
Authors 14
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Johannes Albertus Langendijk corresponding
University Medical Center Groningen · University of Groningen
Affiliation as printed
Department of Radiation Oncology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands
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Maastricht University Medical Centre · Maastro Clinic
Affiliation as printed
Department of Radiation Oncology (MAASTRO clinic), GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, the Netherlands
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Leiden University Medical Center
Affiliation as printed
Department of Radiation Oncology, Leiden University Medical Centre, Leiden, the Netherlands
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Utrecht University · University Medical Center Utrecht
Affiliation as printed
Department of Radiation Oncology, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands
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Utrecht University · University Medical Center Utrecht
Affiliation as printed
Department of Radiation Oncology, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands
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University Medical Center Groningen · University of Groningen
Affiliation as printed
Department of Radiation Oncology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands
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The Netherlands Cancer Institute
Affiliation as printed
Department of Radiation Oncology, the Netherlands Cancer Institute, Amsterdam, the Netherlands
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The Netherlands Cancer Institute
Affiliation as printed
Department of Radiation Oncology, the Netherlands Cancer Institute, Amsterdam, the Netherlands
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Amsterdam University Medical Centers · Cancer Center Amsterdam · Vrije Universiteit Amsterdam
Affiliation as printed
Department of Radiation Oncology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, the Netherlands
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Affiliation as printed
Department of Radiation Oncology, Erasmus Medical Center, Rotterdam, the Netherlands
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Utrecht University · University Medical Center Utrecht
Affiliation as printed
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands
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University Medical Center Groningen · University of Groningen
Affiliation as printed
Department of Radiation Oncology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands
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Maastricht University Medical Centre · Maastro Clinic
Affiliation as printed
Department of Radiation Oncology (MAASTRO clinic), GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, the Netherlands
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Utrecht University · University Medical Center Utrecht
Affiliation as printed
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands
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