Competition Sensing Changes Antibiotic Production in Streptomyces

mBio, vol. 12

Abstract

cells also often reduce their output of antibiotics when grown with competitors, especially under nutrient limitation. Our findings highlight that interactions between the social and resource environments strongly regulate antibiotic production in these medicinally important bacteria.

Authors 5

1. Sanne Westhoff corresponding Aachen Institute of Biology, Leiden University

   Leiden University

   Affiliation as printed

   Institute of Biology, Leiden University, Leiden, The Netherlands

2. Alexander Kloosterman Aachen Institute of Biology, Leiden University

   Leiden University

   Affiliation as printed

   Institute of Biology, Leiden University, Leiden, The Netherlands

3. Stephan F. A. van Hoesel Aachen Institute of Biology, Leiden University

   Leiden University

   Affiliation as printed

   Institute of Biology, Leiden University, Leiden, The Netherlands

4. Gilles P. van Wezel Aachen Institute of Biology, Leiden University

   Leiden University · Netherlands Institute of Ecology

   Affiliation as printed

   Institute of Biology, Leiden University, Leiden, The Netherlands

   Netherlands Institute of Ecology (NIOO-KNAW), Wageningen, The Netherlands

5. Daniel E. Rozen corresponding Aachen Institute of Biology, Leiden University

   Leiden University

   Affiliation as printed

   Institute of Biology, Leiden University, Leiden, The Netherlands