Open Targets Platform: supporting systematic drug–target identification and prioritisation

• pyBiodatafuse: extending interoperability of data using modular queries across biomedical resources

  2026 Bioinformatics article Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access

  2

  citations
• Effector–host interactome map links type III secretion systems in healthy gut microbiomes to immune modulation

  2026 Nature Microbiology article Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access

  4

  citations
• Translational genomics of osteoarthritis in 1,962,069 individuals

  2025 Nature article Medicine Osteoarthritis Treatment and Mechanisms Open access

  85

  citations
• A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models

  2024 Nature Biotechnology article Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Open access

  333

  citations
• A gut meta-interactome map reveals modulation of human immunity by microbiome effectors

  2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access

  5

  citations
• MultiGML: Multimodal graph machine learning for prediction of adverse drug events

  2023 Heliyon article Computer Science Computational Drug Discovery Methods Open access

  22

  citations
• Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy

  2023 Nature Genetics article Medicine Renal Diseases and Glomerulopathies Open access

  191

  citations
• Using a Network-Based Analysis Approach to Investigate the Involvement of S. aureus in the Pathogenesis of Granulomatosis with Polyangiitis

  2023 International Journal of Molecular Sciences article Medicine Vasculitis and related conditions Open access

  1

  citations
• MultiGML: Multimodal Graph Machine Learning for Prediction of Adverse Drug Events

  2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access

  3

  citations
• Genome-wide association study reveals loci with sex-specific effects on plasma bile acids

  2022 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  0

  citations
• Stroke genetics informs drug discovery and risk prediction across ancestries

  2022 Nature article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  598

  citations
• Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility

  2022 Nature Genetics article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access

  202

  citations
• Genome-wide association study of treatment resistant depression highlights shared biology with metabolic traits

  2022 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  3

  citations
• Stroke genetics informs drug discovery and risk prediction across ancestries

  2022 Research Square preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  9

  citations
• Implicating genes, pleiotropy and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

  2021 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  8

  citations
• Sequencing of over 100,000 individuals identifies multiple genes and rare variants associated with Crohns disease susceptibility

  2021 medRxiv preprint Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access

  11

  citations

16 results