Measuring eye deformation between planning and proton beam therapy position using magnetic resonance imaging

Physics and Imaging in Radiation Oncology, vol. 16, pp. 33–36

Abstract

Proton beam therapy (PBT) for uveal melanoma (UM) is performed in sitting position, while the acquisition of the Magnetic resonance (MR)-images for treatment planning is performed in supine position. We assessed the effect of this difference in position on the eye- and tumour- shape. Seven subjects and six UM-patients were scanned in supine and a seating mimicking position. The distances between the tumour/sclera in both positions were calculated. The median distance between both positions was 0.1 mm. Change in gravity direction produced no substantial changes in sclera and tumour shape, indicating that supinely acquired MR-images can be used to plan ocular-PBT.

Authors 8

1. Myriam G. Jaarsma‐Coes corresponding Aachen Ophthalmology Radiology C. J. Gorter Center for High Field MRI

   Leiden University · Leiden University Medical Center

   Affiliation as printed

   Ophthalmology, Leiden University Medical Centre, Leiden, Netherlands

   Radiology, C.J. Gorter Centre for High Field MRI, Leiden University Medical Centre, Leiden, Netherlands

2. Marina Marinkovic Aachen Ophthalmology

   Leiden University · Leiden University Medical Center

   Affiliation as printed

   Ophthalmology, Leiden University Medical Centre, Leiden, Netherlands

3. Eleftheria Astreinidou Aachen Radiotherapy

   Leiden University · Leiden University Medical Center

   Affiliation as printed

   Radiotherapy, Leiden University Medical Centre, Leiden, Netherlands

4. Megan S. Schuurmans Aachen Radiology C. J. Gorter Center for High Field MRI

   Leiden University · Leiden University Medical Center

   Affiliation as printed

   Radiology, C.J. Gorter Centre for High Field MRI, Leiden University Medical Centre, Leiden, Netherlands

5. Femke P. Peters Aachen Radiotherapy

   Leiden University · Leiden University Medical Center

   Affiliation as printed

   Radiotherapy, Leiden University Medical Centre, Leiden, Netherlands

6. Gregorius P. M. Luyten Aachen Ophthalmology

   Leiden University · Leiden University Medical Center

   Affiliation as printed

   Ophthalmology, Leiden University Medical Centre, Leiden, Netherlands

7. Coen R. N. Rasch Aachen Radiotherapy

   Leiden University · Leiden University Medical Center

   Affiliation as printed

   Radiotherapy, Leiden University Medical Centre, Leiden, Netherlands

8. Jan‐Willem M. Beenakker Aachen Ophthalmology Radiology C. J. Gorter Center for High Field MRI

   Leiden University · Leiden University Medical Center

   Affiliation as printed

   Ophthalmology, Leiden University Medical Centre, Leiden, Netherlands

   Radiology, C.J. Gorter Centre for High Field MRI, Leiden University Medical Centre, Leiden, Netherlands