Deconvoluting Lipid Nanoparticle Structure for Messenger RNA Delivery

• Investigating the stability of RNA-lipid nanoparticles in biological fluids: Unveiling its crucial role for understanding LNP performance

  2025 Journal of Controlled Release article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access

  68

  citations
• On the Influence of Fabrication Methods and Materials for mRNA‐LNP Production: From Size and Morphology to Internal Structure and mRNA Delivery Performance In Vitro and In Vivo

  2024 Advanced Healthcare Materials article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access

  25

  citations
• Liquid crystalline inverted lipid phases encapsulating siRNA enhance lipid nanoparticle mediated transfection

  2024 Nature Communications article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access

  120

  citations
• Biological recognition and cellular trafficking of targeted RNA-lipid nanoparticles

  2023 Current Opinion in Biotechnology review Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access

  25

  citations
• Phase‐Separated Lipid‐Based Nanoparticles: Selective Behavior at the Nano‐Bio Interface

  2023 Advanced Materials article Materials Science Nanoparticle-Based Drug Delivery Open access cited by 1 patent

  12

  citations
• Fusogenic Coiled-Coil Peptides Enhance Lipid Nanoparticle-Mediated mRNA Delivery upon Intramyocardial Administration

  2023 ACS Nano article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access cited by 1 patent

  46

  citations
• In vitro and in vivo evaluation of clinically-approved ionizable cationic lipids shows divergent results between mRNA transfection and vaccine efficacy

  2023 Biomedicine & Pharmacotherapy article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access

  85

  citations
• Lipid nanoparticle-based mRNA candidates elicit potent T cell responses

  2022 Biomaterials Science article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access cited by 6 patents

  51

  citations
• Anionic Lipid Nanoparticles Preferentially Deliver mRNA to the Hepatic Reticuloendothelial System

  2022 Advanced Materials article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access cited by 1 patent

  191

  citations
• mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability

  2021 International Journal of Pharmaceutics article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access cited by 179 patents

  1,549

  citations

10 results