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The Evolution of Data Fusion Methodologies Developed to Reconstruct Coronary Artery Geometry From Intravascular Imaging and Coronary Angiography Data: A Comprehensive Review

Frontiers in Cardiovascular Medicine, vol. 7, pp. 33

Abstract

Understanding the mechanisms that regulate atherosclerotic plaque formation and evolution is a crucial step for developing treatment strategies that will prevent plaque progression and reduce cardiovascular events. Advances in signal processing and the miniaturization of medical devices have enabled the design of multimodality intravascular imaging catheters that allow complete and detailed assessment of plaque morphology and biology. However, a significant limitation of these novel imaging catheters is that they provide two-dimensional (2D) visualization of the lumen and vessel wall and thus they cannot portray vessel geometry and 3D lesion architecture. To address this limitation computer-based methodologies and user-friendly software have been developed. These are able to off-line process and fuse intravascular imaging data with X-ray or computed tomography coronary angiography (CTCA) to reconstruct coronary artery anatomy. The aim of this review article is to summarize the evolution in the field of coronary artery modeling; we thus present the first methodologies that were developed to model vessel geometry, highlight the modifications introduced in revised methods to overcome the limitations of the first approaches and discuss the challenges that need to be addressed, so these techniques can have broad application in clinical practice and research.

Authors 12

  1. National Health Service · Barts Health NHS Trust

    Affiliation as printed

    Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, London, United Kingdom

  2. University College London

    Affiliation as printed

    Institute of Cardiovascular Sciences, University College London, London, United Kingdom

  3. National Health Service · Queen Mary University of London · Barts Health NHS Trust

    Affiliation as printed

    Centre for Cardiovascular Medicine and Device Innovation, Queen Mary University London, London, United Kingdom

    Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, London, United Kingdom

  4. Imperial College London

    Affiliation as printed

    Faculty of Medicine, National Heart & Lung Institute, Imperial College London, London, United Kingdom

  5. Leiden University Medical Center

    Affiliation as printed

    Department of Radiology, Leiden University Medical Center, Leiden, Netherlands

  6. National Health Service · Queen Mary University of London · Barts Health NHS Trust

    Affiliation as printed

    Centre for Cardiovascular Medicine and Device Innovation, Queen Mary University London, London, United Kingdom

    Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, London, United Kingdom

  7. Queen Mary University of London

    Affiliation as printed

    Centre for Cardiovascular Medicine and Device Innovation, Queen Mary University London, London, United Kingdom

  8. Erasmus MC

    Affiliation as printed

    Erasmus University Medical Center, Rotterdam, Netherlands

  9. National Health Service · Queen Mary University of London · Barts Health NHS Trust

    Affiliation as printed

    Centre for Cardiovascular Medicine and Device Innovation, Queen Mary University London, London, United Kingdom

    Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, London, United Kingdom

  10. University College London

    Affiliation as printed

    Department of Mechanical Engineering, University College London, London, United Kingdom

  11. National Health Service · Queen Mary University of London · Barts Health NHS Trust

    Affiliation as printed

    Centre for Cardiovascular Medicine and Device Innovation, Queen Mary University London, London, United Kingdom

    Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, London, United Kingdom

  12. Christos V. Bourantas corresponding

    National Health Service · Queen Mary University of London · Barts Health NHS Trust · University College London

    Affiliation as printed

    Centre for Cardiovascular Medicine and Device Innovation, Queen Mary University London, London, United Kingdom

    Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, London, United Kingdom

    Institute of Cardiovascular Sciences, University College London, London, United Kingdom

Cited by 21 stored of 22

Cited by patents worldwide 1 (Lens.org)

References 83