Engineering new catalytic activities in enzymes

• Automated in vivo enzyme engineering accelerates biocatalyst optimization

  2024 Nature Communications article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access

  87

  citations
• Advances in One-Pot Chiral Amine Synthesis Enabled by Amine Transaminase Cascades: Pushing the Boundaries of Complexity

  2023 ACS Catalysis article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access

  61

  citations
• Evolutionary Engineering of a Cp*Rh(III) Complex-Linked Artificial Metalloenzyme with a Chimeric β-Barrel Protein Scaffold

  2023 Journal of the American Chemical Society article Chemistry Cyclopropane Reaction Mechanisms Open access

  28

  citations
• Engineering and emerging applications of artificial metalloenzymes with whole cells

  2021 Nature Catalysis article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization

  84

  citations
• Computer-aided enzymatic retrosynthesis

  2021 Nature Catalysis article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization

  10

  citations
• Applied biocatalysis beyond just buffers – from aqueous to unconventional media. Options and guidelines

  2021 Green Chemistry article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access

  153

  citations
• Directed Evolution of a Cp*RhIII‐Linked Biohybrid Catalyst Based on a Screening Platform with Affinity Purification

  2020 ChemBioChem article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access

  20

  citations
• Incorporation of a Cp*Rh(III)-dithiophosphate Cofactor with Latent Activity into a Protein Scaffold Generates a Biohybrid Catalyst Promoting C(sp2)–H Bond Functionalization

  2020 Inorganic Chemistry article Chemistry Organometallic Complex Synthesis and Catalysis Open access

  20

  citations

8 results