A

COvalent monolayer patterns in Microfluidics by PLasma etching Open Technology – COMPLOT

The Analyst, vol. 145, pp. 1629–1635

Abstract

Plasma microcontact patterning (PμCP) and replica molding were combined to make PDMS/glass microfluidic devices with β-cyclodextrin (β-CD) patterns attached covalently on the glass surface inside microchannels. The supramolecular reactivity, reusability and association constant of β-CD with Cy5-Ad2 was tested by analyzing signal-to-noise ratios of patterns vs. spacing with fluorescence microscopy.

Authors 7

  1. Leiden University · Leiden University Medical Center · Wetsus, European Centre of Excellence for Sustainable Water Technology · Wageningen University & Research

    Affiliation as printed

    6708 WG Wageningen

    Laboratory of BioNanoTechnology

    Wageningen University and Research

    Wetsus

    the Netherlands

    Interventional Molecular Imaging, Department of Radiology, Leiden University and Medical Centre, 2300 RC Leiden, the Netherlands

    Laboratory of BioNanoTechnology, Wageningen University and Research, Bornse Weilanden 9, 6708 WG Wageningen, the Netherlands

    Wetsus, European Centre of Excellence for Sustainable Water Technology, Oostergoweg 9, 8911 MA Leeuwarden, the Netherlands

  2. Wageningen University & Research

    Affiliation as printed

    6708 WG Wageningen

    Laboratory of BioNanoTechnology

    Wageningen University and Research

    the Netherlands

    Laboratory of BioNanoTechnology, Wageningen University and Research, Bornse Weilanden 9, 6708 WG Wageningen, the Netherlands

  3. Leiden University · Leiden University Medical Center · Wageningen University & Research

    Affiliation as printed

    6708 WG Wageningen

    Interventional Molecular Imaging

    Laboratory of BioNanoTechnology

    Wageningen University and Research

    the Netherlands

    Interventional Molecular Imaging, Department of Radiology, Leiden University and Medical Centre, 2300 RC Leiden, the Netherlands

    Laboratory of BioNanoTechnology, Wageningen University and Research, Bornse Weilanden 9, 6708 WG Wageningen, the Netherlands

  4. Wetsus, European Centre of Excellence for Sustainable Water Technology

    Affiliation as printed

    8911 MA Leeuwarden

    European Centre of Excellence for Sustainable Water Technology

    Wetsus

    the Netherlands

    Wetsus, European Centre of Excellence for Sustainable Water Technology, Oostergoweg 9, 8911 MA Leeuwarden, the Netherlands

  5. Leiden University · Leiden University Medical Center · Wageningen University & Research

    Affiliation as printed

    6708 WG Wageningen

    Interventional Molecular Imaging

    Laboratory of BioNanoTechnology

    Wageningen University and Research

    the Netherlands

    Interventional Molecular Imaging, Department of Radiology, Leiden University and Medical Centre, 2300 RC Leiden, the Netherlands

    Laboratory of BioNanoTechnology, Wageningen University and Research, Bornse Weilanden 9, 6708 WG Wageningen, the Netherlands

  6. Leiden University · Leiden University Medical Center · Wageningen University & Research

    Affiliation as printed

    6708 WG Wageningen

    Interventional Molecular Imaging

    Laboratory of BioNanoTechnology

    Wageningen University and Research

    the Netherlands

    Interventional Molecular Imaging, Department of Radiology, Leiden University and Medical Centre, 2300 RC Leiden, the Netherlands

    Laboratory of BioNanoTechnology, Wageningen University and Research, Bornse Weilanden 9, 6708 WG Wageningen, the Netherlands

  7. Vittorio Saggiomo corresponding

    Wageningen University & Research

    Affiliation as printed

    6708 WG Wageningen

    Laboratory of BioNanoTechnology

    Wageningen University and Research

    the Netherlands

    Laboratory of BioNanoTechnology, Wageningen University and Research, Bornse Weilanden 9, 6708 WG Wageningen, the Netherlands

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References 35