Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease

• Somatic mutations reveal the ontogeny of microglia in human ageing

  2026 Nature article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms

  3

  citations
• gsQTL: Associating genetic risk variants with gene sets by exploiting their shared variability

  2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  0

  citations
• Morphotype-specific calcium signaling in human microglia

  2024 Journal of Neuroinflammation article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access

  10

  citations
• Morphotype-specific calcium signaling in human microglia

  2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Neuroinflammation and Neurodegeneration Mechanisms

  0

  citations
• Single-cell, whole-embryo phenotyping of mammalian developmental disorders

  2023 Nature article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  41

  citations
• Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro

  2023 Nature Immunology article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access

  169

  citations
• Single-cell RNA sequencing data reveals rewiring of transcriptional relationships in Alzheimer’s Disease associated with risk variants

  2023 medRxiv preprint Medicine Alzheimer's disease research and treatments Open access

  3

  citations
• Single cell, whole embryo phenotyping of pleiotropic disorders of mammalian development

  2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  5

  citations
• Identifying aging and Alzheimer’s disease associated somatic mutations in excitatory neurons from the human frontal cortex using whole genome sequencing and single cell RNA sequencing data

  2022 medRxiv preprint Medicine Alzheimer's disease research and treatments Open access

  2

  citations
• A resource for generating and manipulating human microglial states in vitro

  2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access

  12

  citations
• Co-expression patterns of microglia markers Iba1, TMEM119 and P2RY12 in Alzheimer's disease

  2022 Neurobiology of Disease article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access

  190

  citations
• Microglial inclusions and neurofilament light chain release follow neuronal α-synuclein lesions in long-term brain slice cultures

  2021 Molecular Neurodegeneration article Medicine Parkinson's Disease Mechanisms and Treatments Open access

  38

  citations
• Co-expression patterns of microglia markers Iba1, TMEM119 and P2RY12 in Alzheimer’s disease

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access

  8

  citations
• Iron loading is a prominent feature of activated microglia in Alzheimer’s disease patients

  2021 Acta Neuropathologica Communications article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access

  184

  citations
• Comparative Analysis Identifies Similarities between the Human and Murine Microglial Sensomes

  2021 International Journal of Molecular Sciences article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access

  40

  citations
• Iron-loading is a prominent feature of activated microglia in Alzheimer’s disease patients

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access

  8

  citations

16 results