Guidelines for performing Mendelian randomization investigations

• MR-link-2: pleiotropy robust cis Mendelian randomization validated in three independent reference datasets of causality

  2025 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  20

  citations
• The impact of common and rare genetic variants on bradyarrhythmia development

  2025 Nature Genetics article Medicine Cardiac electrophysiology and arrhythmias Open access

  25

  citations
• Genomic Landscape of Thrombosis Recurrence Risk Across Venous Thromboembolism Subtypes

  2024 medRxiv preprint Medicine Venous Thromboembolism Diagnosis and Management Open access

  0

  citations
• GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification

  2023 Nature Genetics article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  107

  citations
• Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study

  2022 British Journal of Sports Medicine article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  100

  citations
• Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome

  2021 Nature Communications article Medicine Parkinson's Disease Mechanisms and Treatments Open access cited by 1 patent

  209

  citations
• Random glucose GWAS in 493,036 individuals provides insights into diabetes pathophysiology, complications and treatment stratification

  2021 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  10

  citations
• Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

  2021 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  172

  citations
• Multivariate genomic scan implicates novel loci and haem metabolism in human ageing

  2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access cited by 2 patents

  145

  citations

9 results

• Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids

  2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  61

  citations

1 result