Bulk tissue cell type deconvolution with multi-subject single-cell expression reference

• Longitudinal analysis of lipid changes in the sciatic nerve caused by overexpression of PMP22 in murine models of CMT1A

  2026 Journal of Lipid Research article Neuroscience Hereditary Neurological Disorders Open access

  1

  citations
• Carotid plaque macrophage burden and inflammatory lipid-associated macrophage markers predict secondary major adverse cardiovascular events after endarterectomy

  2026 European Heart Journal article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access

  11

  citations
• Tissue‐specific methylomic responses to a lifestyle intervention in older adults associate with metabolic and physiological health improvements

  2024 Aging Cell article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access

  3

  citations
• A transcriptomic based deconvolution framework for assessing differentiation stages and drug responses of AML

  2024 npj Precision Oncology article Medicine Acute Myeloid Leukemia Research Open access

  14

  citations
• Single cell guided deconvolution of bulk transcriptomics recapitulates differentiation stages of acute myeloid leukemia and predicts drug response

  2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Acute Myeloid Leukemia Research Open access

  1

  citations
• Correcting Differential Gene Expression Analysis for Cyto—Architectural Alterations in Substantia Nigra of Parkinson’s Disease Patients Reveals Known and Potential Novel Disease—Associated Genes and Pathways

  2022 Cells article Medicine Parkinson's Disease Mechanisms and Treatments Open access

  1

  citations
• Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments

  2021 Clinical Cancer Research article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  18

  citations
• Transcriptomic-based clustering of advanced atherosclerotic plaques identifies subgroups of plaques with differential underlying biology that associate with clinical presentation

  2021 medRxiv preprint Medicine Cerebrovascular and Carotid Artery Diseases Open access

  7

  citations
• Correcting differential gene expression analysis for cyto-architectural alterations in substantia nigra of Parkinson’s disease patients reveals known and potential novel disease-associated genes and pathways

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Parkinson's Disease Mechanisms and Treatments Open access

  0

  citations
• Deconvolution of cellular subsets in human tissue based on targeted DNA methylation analysis at individual CpG sites

  2020 BMC Biology article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access cited by 7 patents

  93

  citations
• Deconvolution of cellular subsets in human tissue based on targeted DNA methylation analysis at individual CpG sites

  2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access

  2

  citations

11 results