destiny : diffusion maps for large-scale single-cell data in R

• An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying SFPQ-TFE3 driven translocation RCC

  2025 iScience article Medicine Renal cell carcinoma treatment Open access

  5

  citations
• Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells

  2024 Nature Biotechnology article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access

  30

  citations
• High-dimensional single-cell analysis of human natural killer cell heterogeneity

  2024 Nature Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access

  278

  citations
• Characterization of the human fetal gonad and reproductive tract by single-cell transcriptomics

  2024 Developmental Cell article Biochemistry, Genetics and Molecular Biology Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities Open access

  31

  citations
• Mapping cardiac remodeling in chronic kidney disease

  2023 Science Advances article Medicine Cardiac Fibrosis and Remodeling Open access

  25

  citations
• DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age

  2023 Nature Communications article Medicine Hematopoietic Stem Cell Transplantation Open access

  27

  citations
• Treatment effects of soluble guanylate cyclase modulation on diabetic kidney disease at single-cell resolution

  2023 Cell Reports Medicine article Medicine Chronic Kidney Disease and Diabetes Open access

  35

  citations
• Next-Generation Morphometry for pathomics-data mining in histopathology

  2023 Nature Communications article Computer Science AI in cancer detection Open access

  141

  citations
• DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age

  2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Hematopoietic Stem Cell Transplantation Open access

  1

  citations
• Next-Generation Morphometry for pathomics-data mining in histopathology

  2022 Research Square preprint Computer Science AI in cancer detection Open access

  6

  citations
• Complement activation induces excessive T cell cytotoxicity in severe COVID-19

  2021 Cell article Medicine COVID-19 Clinical Research Studies Open access cited by 2 patents

  215

  citations
• Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen

  2021 Nature Communications article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  141

  citations
• Complement activation induces excessive T cell cytotoxicity in severe COVID-19

  2021 medRxiv preprint Medicine COVID-19 Clinical Research Studies Open access

  3

  citations
• Spatiotemporal heterogeneity of glioblastoma is dictated by microenvironmental interference

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Glioma Diagnosis and Treatment Open access

  12

  citations
• Spatiotemporal heterogeneity of glioblastoma is dictated by microenvironmental interference

  2021 Research Square preprint Medicine Glioma Diagnosis and Treatment Open access

  4

  citations
• Complement Activation Induces Excessive T Cell Cytotoxicity in Severe COVID-19

  2021 SSRN Electronic Journal preprint Medicine COVID-19 Clinical Research Studies Open access

  22

  citations
• Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis

  2020 Cell Metabolism article Biochemistry, Genetics and Molecular Biology FOXO transcription factor regulation Open access

  178

  citations
• A Comprehensive Workflow for Applying Single-Cell Clustering and Pseudotime Analysis to Flow Cytometry Data

  2020 The Journal of Immunology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  56

  citations

18 results