Machine learning-assisted directed protein evolution with combinatorial libraries

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• Engineering of Substrate Tunnel of P450 CYP116B3 though Machine Learning

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• Deep learning guided enzyme engineering of Thermobifida fusca cutinase for increased PET depolymerization

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• Rational evolution of a recombinant DNA polymerase for efficient incorporation of unnatural nucleotides by dual-site boosting

  2022 Research Square preprint Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access

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• Rational evolution of a recombinant DNA polymerase for efficient incorporation of unnatural nucleotides by dual-site boosting

  2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access

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• Protein Engineering by Efficient Sequence Space Exploration Through Combination of Directed Evolution and Computational Design Methodologies

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• PyPEF—An Integrated Framework for Data-Driven Protein Engineering

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• Machine learning-assisted enzyme engineering

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10 results