Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development

• PHLOWER leverages single-cell multimodal data to infer complex, multi-branching cell differentiation trajectories

  2025 Nature Methods article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  9

  citations
• The roles of hyaluronan in kidney development, physiology and disease

  2024 Nature Reviews Nephrology review Biochemistry, Genetics and Molecular Biology Proteoglycans and glycosaminoglycans research Open access

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• Characterization of the human fetal gonad and reproductive tract by single-cell transcriptomics

  2024 Developmental Cell article Biochemistry, Genetics and Molecular Biology Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities Open access

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• Spatial dynamic metabolomics identifies metabolic cell fate trajectories in human kidney differentiation

  2022 Cell stem cell article Biochemistry, Genetics and Molecular Biology Renal and related cancers Open access

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• Characterization of the human fetal rete region by single cell transcriptional analysis of gonads and mesonephros/epididymis

  2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Sperm and Testicular Function Open access

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• Mapping the human kidney using single-cell genomics

  2022 Nature Reviews Nephrology review Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  71

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• Phiclust: a clusterability measure for single-cell transcriptomics reveals phenotypic subpopulations

  2022 Genome biology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  19

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• How a cell decides its own fate: a single-cell view of molecular mechanisms and dynamics of cell-type specification

  2021 Biochemical Society Transactions article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  7

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• Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing

  2021 npj Regenerative Medicine article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  60

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• Revealing the spatio-phenotypic patterning of cells in healthy and tumor tissues with mLSR-3D and STAPL-3D

  2021 Nature Biotechnology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access cited by 4 patents

  34

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• A clusterability measure for single-cell transcriptomics reveals phenotypic subpopulations

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  0

  citations

11 results