The PI3K Pathway in Human Disease

• Associations Between Short‐Term Changes in Disease Activity and Long‐Term Clinical Outcomes in Activated Phosphoinositide 3‐Kinase Delta Syndrome

  2026 Journal of Immunology Research article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access

  0

  citations
• Natural history of clinical manifestations in activated phosphoinositide 3-kinase δ syndrome (APDS): Time-to-event analyses using the European Society for Immunodeficiencies-APDS registry

  2025 Clinical Immunology article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access

  3

  citations
• Reversion of aortic valve cells calcification by activation of Notch signalling via histone acetylation induction

  2025 Signal Transduction and Targeted Therapy article Medicine Cardiac Valve Diseases and Treatments Open access

  4

  citations
• Systematic literature reviews to identify epidemiological, clinical, economic and health-related quality of life evidence in activated PI3Kδ syndrome (APDS)

  2025 BMC Immunology review Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access

  1

  citations
• Value contribution of leniolisib in the Treatment of Activated PI3Kδ syndrome (APDS) in Spain using Multi-Criteria Decision Analysis (MCDA)

  2025 Global & Regional Health Technology Assessment article Economics, Econometrics and Finance Health Systems, Economic Evaluations, Quality of Life Open access

  2

  citations
• Comparative efficacy of leniolisib (CDZ173) versus standard of care on rates of respiratory tract infection and serum immunoglobulin M (IgM) levels among individuals with activated phosphoinositide 3-kinase delta (PI3Kδ) syndrome (APDS): an externally controlled study

  2024 Clinical & Experimental Immunology article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access

  7

  citations
• European Association of Neuro-Oncology guideline on molecular testing of meningiomas for targeted therapy selection

  2024 Neuro-Oncology article Medicine Meningioma and schwannoma management Open access

  38

  citations
• Farnesol Inhibits PI3 Kinase Signaling and Inflammatory Gene Expression in Primary Human Renal Epithelial Cells

  2023 Biomedicines article Medicine Natural Compounds in Disease Treatment Open access

  2

  citations
• PI3Kδ Pathway Dysregulation and Unique Features of Its Inhibition by Leniolisib in Activated PI3Kδ Syndrome and Beyond

  2023 The Journal of Allergy and Clinical Immunology In Practice article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access

  27

  citations
• Functional evidence (II) protein and enzyme function

  2021 Elsevier eBooks book-chapter Biochemistry, Genetics and Molecular Biology Genomics and Rare Diseases

  1

  citations

10 results