A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response

• Microglial 5-LOX-activating protein antagonism alleviates leukotriene-driven neuroinflammation

  2026 Acta Neuropathologica article Medicine Multiple Sclerosis Research Studies Open access

  0

  citations
• Comparative lipidomics of iPSC-derived microglia protocols reveal lipid droplet and immune differences mediated by media composition

  2026 Stem Cell Reports article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access

  1

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• De novo H3.3K27M-altered diffuse midline glioma in human brainstem organoids to dissect GD2 CAR T cell function

  2026 Nature Cancer article Medicine Glioma Diagnosis and Treatment Open access

  14

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• De novo H3.3K27M-altered Diffuse Midline Glioma in human brainstem organoids to dissect GD2 CAR T cell function

  2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Glioma Diagnosis and Treatment Open access

  0

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• The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases

  2025 Nature Metabolism article Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access

  29

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• The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4

  2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Alzheimer's disease research and treatments Open access

  22

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• Human cortical spheroids with a high diversity of innately developing brain cell types

  2023 Stem Cell Research & Therapy article Neuroscience Neurogenesis and neuroplasticity mechanisms Open access

  15

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• Pluripotent stem cell strategies for rebuilding the human brain

  2022 Frontiers in Aging Neuroscience article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 1 patent

  15

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• Iron accumulation induces oxidative stress, while depressing inflammatory polarization in human iPSC-derived microglia

  2022 Stem Cell Reports article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access

  70

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• Stem Cell-Based Disease Models for Inborn Errors of Immunity

  2021 Cells article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access

  1

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• Generation of pure monocultures of human microglia-like cells from induced pluripotent stem cells

  2020 Stem Cell Research article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access cited by 1 patent

  53

  citations
• Generation and Functional Characterization of Monocytes and Macrophages Derived from Human Induced Pluripotent Stem Cells

  2020 Current Protocols in Stem Cell Biology article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 3 patents

  49

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12 results