Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

• HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes

  2025 Cell Metabolism article Medicine Pancreatic function and diabetes Open access

  17

  citations
• GWAS of CRP response to statins further supports the role of APOE in statin response: A GIST consortium study

  2025 Pharmacological Research article Medicine Lipoproteins and Cardiovascular Health Open access

  3

  citations
• Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

  2024 Nature article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  594

  citations
• Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization

  2023 Wellcome Open Research article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  7

  citations
• Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

  2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  44

  citations
• Genetic insights into resting heart rate and its role in cardiovascular disease

  2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  36

  citations
• A multivariate genome-wide association study of psycho-cardiometabolic multimorbidity

  2023 PLoS Genetics article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  20

  citations
• Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications

  2023 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  21

  citations
• Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

  2022 Nature Genetics article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  773

  citations
• Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts

  2022 Diabetes Care article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  72

  citations
• Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

  2022 Cell Reports Medicine article Medicine Diabetes, Cardiovascular Risks, and Lipoproteins Open access cited by 1 patent

  94

  citations
• Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease

  2021 Nature Communications article Medicine Lipoproteins and Cardiovascular Health Open access

  143

  citations
• Germline genetic contribution to the immune landscape of cancer

  2021 Immunity article Medicine Cancer Immunotherapy and Biomarkers Open access cited by 1 patent

  182

  citations
• Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

  2020 Nature Genetics review Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access cited by 2 patents

  248

  citations
• Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

  2020 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  27

  citations
• The endothelial function biomarker soluble E‐selectin is associated with nonalcoholic fatty liver disease

  2020 Liver International article Medicine Liver Disease Diagnosis and Treatment Open access

  37

  citations

16 results