MendelianRandomization: an R package for performing Mendelian randomization analyses using summarized data

• Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes

  2025 Nature Genetics article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  57

  citations
• Biological pathways underlying the relationship between childhood maltreatment and Multimorbidity: A two-step, multivariable Mendelian randomisation study

  2025 Brain Behavior and Immunity article Psychology Child Abuse and Trauma Open access

  4

  citations
• Bidirectional Mendelian Randomization Highlights Causal Relationships Between Circulating INHBC and Multiple Cardiometabolic Diseases and Traits

  2024 Diabetes article Medicine Adipokines, Inflammation, and Metabolic Diseases Open access cited by 2 patents

  11

  citations
• Genome-wide characterization of circulating metabolic biomarkers

  2024 Nature article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  263

  citations
• Childhood abuse v. neglect and risk for major psychiatric disorders

  2023 Psychological Medicine article Psychology Child Abuse and Trauma Open access

  35

  citations
• Mapping the aetiological foundations of the heart failure spectrum using human genetics

  2023 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  6

  citations
• Genetic insights into resting heart rate and its role in cardiovascular disease

  2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  36

  citations
• Circulating metabolites modulated by diet are associated with depression

  2023 Molecular Psychiatry article Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access

  56

  citations
• Obesity, Fat Distribution and Risk of Cancer in Women and Men: A Mendelian Randomisation Study

  2022 Nutrients article Medicine Cancer Risks and Factors Open access

  42

  citations
• Genome-wide characterization of circulating metabolic biomarkers reveals substantial pleiotropy and novel disease pathways

  2022 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  3

  citations
• Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study

  2022 British Journal of Sports Medicine article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  100

  citations
• Variants in the GPR146 Gene Are Associated With a Favorable Cardiometabolic Risk Profile

  2022 Arteriosclerosis Thrombosis and Vascular Biology article Medicine Lipid metabolism and disorders Open access

  12

  citations
• Circulating metabolites modulated by diet are causally associated with depression

  2022 Research Square preprint Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access

  0

  citations
• Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus

  2022 Nature Communications article Medicine Blood Coagulation and Thrombosis Mechanisms Open access

  22

  citations
• Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome

  2021 Nature Communications article Medicine Parkinson's Disease Mechanisms and Treatments Open access cited by 1 patent

  209

  citations
• Telomere length and metabolic syndrome traits: A Mendelian randomisation study

  2021 Aging Cell article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  40

  citations
• Multivariate genomic scan implicates novel loci and haem metabolism in human ageing

  2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access cited by 2 patents

  145

  citations
• Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

  2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  845

  citations

18 results