CD8+ T Cells Orchestrate pDC-XCR1+ Dendritic Cell Spatial and Functional Cooperativity to Optimize Priming

• Stem-like PD-1 + TCF-1 + CD8 + T cells result from helpless priming and rely on CD4 + T-cell help to complete their cytotoxic effector differentiation

  2026 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology T-cell and B-cell Immunology Open access

  2

  citations
• CD4+ T-cell help delivery to monocyte-derived dendritic cells promotes effector differentiation of helper and cytotoxic T cells

  2025 Immunology Letters article Immunology and Microbiology Immunotherapy and Immune Responses Open access

  7

  citations
• The importance of type I interferon in orchestrating the cytotoxic T-cell response to cancer

  2024 Immunology Letters article Immunology and Microbiology Immunotherapy and Immune Responses Open access

  19

  citations
• Human CD34+-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8+ T cell and NK cell responses in vitro and in vivo

  2023 Cellular and Molecular Life Sciences article Immunology and Microbiology Immunotherapy and Immune Responses Open access

  4

  citations
• GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

  2023 Nature article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access

  226

  citations
• CD4+ helper T cells endow cDC1 with cancer-impeding functions in the human tumor micro-environment

  2023 Nature Communications article Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 3 patents

  92

  citations
• Plasmacytoid Dendritic Cells Facilitate Th Cell Cytokine Responses throughout Schistosoma mansoni Infection

  2021 ImmunoHorizons article Immunology and Microbiology Parasites and Host Interactions Open access

  12

  citations
• Distinct antigen uptake receptors route to the same storage compartments for cross‐presentation in dendritic cells

  2021 Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access

  13

  citations
• Mechanism of action of PD‐1 receptor/ligand targeted cancer immunotherapy

  2021 European Journal of Immunology article Medicine Cancer Immunotherapy and Biomarkers Open access

  62

  citations
• Clinically applicable CD34+-derived blood dendritic cell subsets exhibit key subset-specific features and potently boost anti-tumor T and NK cell responses

  2021 Cancer Immunology Immunotherapy article Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 2 patents

  26

  citations
• Helpless Priming Sends CD8+ T Cells on the Road to Exhaustion

  2020 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access

  56

  citations

11 results