A step-by-step workflow for low-level analysis of single-cell RNA-seq data

• CaClust: linking genotype to transcriptional heterogeneity of follicular lymphoma using BCR and exomic variants

  2024 Genome biology article Medicine Lymphoma Diagnosis and Treatment Open access

  2

  citations
• Mapping the glial transcriptome in Huntington’s disease using snRNAseq: selective disruption of glial signatures across brain regions

  2024 Acta Neuropathologica Communications article Neuroscience Genetic Neurodegenerative Diseases Open access

  11

  citations
• Distinct spatiotemporal dynamics of CD8+ T cell-derived cytokines in the tumor microenvironment

  2024 Cancer Cell article Medicine Cancer Immunotherapy and Biomarkers Open access

  92

  citations
• Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells

  2022 Science Advances article Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access

  39

  citations
• Spatial multi-omic map of human myocardial infarction

  2022 Nature article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  764

  citations
• Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer

  2022 Nature Genetics article Biochemistry, Genetics and Molecular Biology Cancer Genomics and Diagnostics Open access

  98

  citations
• Integrating bulk and single‐cell RNA sequencing reveals cellular heterogeneity and immune infiltration in hepatocellular carcinoma

  2022 Molecular Oncology article Medicine Cancer Immunotherapy and Biomarkers Open access

  58

  citations
• Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice

  2022 Nature Communications article Biochemistry, Genetics and Molecular Biology Calcium signaling and nucleotide metabolism Open access cited by 1 patent

  76

  citations
• Phiclust: a clusterability measure for single-cell transcriptomics reveals phenotypic subpopulations

  2022 Genome biology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  19

  citations
• Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

  2022 Cell article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access cited by 4 patents

  1,021

  citations
• SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

  2021 Cell article Medicine COVID-19 Clinical Research Studies Open access cited by 5 patents

  523

  citations
• Therapeutic depletion of CCR8 + tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy

  2021 Journal for ImmunoTherapy of Cancer article Medicine Cancer Immunotherapy and Biomarkers Open access cited by 26 patents

  215

  citations
• Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data

  2020 Genome biology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  367

  citations

13 results